Trent Vale is a suburb located on the outskirts of Stoke-on-Trent in Staffordshire, England. It is bordered on the south by Hanford, to the west by Clayton, to the north by Newcastle-under-Lyme, to the southeast by Oakhill and Penkhull to the northeast. The ward it is under is called 'Springfields and Trent Vale'. The population of the ward at the 2011 census was 6,816.

The area is home to the Clayton Wood Training Ground, owned by Stoke City FC. Employment is provided locally by the Royal Stoke University Hospital.

Trent Vale has a church called St John the Evangelist Church, Trent Vale erected in the early Gothic style in 1843. The architect was Philip Wooton.

The main road through Trent Vale is the A34, which runs from north to south through the main centre of Trent Vale.