Trenton High School is a public high school in Trenton, Michigan, one of four schools in the Trenton Public School District. The school serves the city of Trenton and is a magnet school for special education students, specifically for those with hearing disabilities, from across Downriver. Enrollment for the 2012-13 school year was about 1200.

• Jim Diamond is an American music producer, musician, and runs Ghetto Recorders studio, formerly located in Detroit, MI.
• Ann Marie Lipinski, former Chicago Tribune editor and Pulitzer Prize winner, who was editor of the Trojan Trumpet [1], graduated in 1974.
• Anthony Bass, current Toronto Blue Jays relief pitcher.
• Bradley A. Smith, Law professor, a Clinton appointee to the Federal Election Commission, elected Chairman of the Commission in 2004, was born and raised in Trenton, elected Senior Class President, and graduated Trenton High in 1976.
• Mary Lynn Rajskub, comedian and actress, was born and raised in Trenton, and graduated from Trenton High School in 1989.
• J. J. Putz, a relief pitcher for the Seattle Mariners, New York Mets, Chicago White Sox and Arizona Diamondbacks as well as a 2007 MLB All-Star Game participant, was raised in Trenton, and graduated from Trenton High School in 1995.
• Professional Comedian Tim Slagle was raised in Trenton, and graduated Trenton High in 1976
• Psychobilly frontman Jim Leedy, of the cult band Elvis Hitler was born and raised in Trenton, and graduated Trenton High in 1979.
• Science fiction author Sarah Zettel was raised in Trenton and is a 1984 graduate of Trenton High School.
• Toronto Blue Jays starting pitcher Matt Shoemaker grew up in Trenton, and graduated from Trenton High School in 2004.
• Andy Greene, professional hockey player for the New York Islanders [2]
• Tom Burkhard is American television producer and writer.
• Former NHL player Larry DePalma was born in Trenton and is a 1983 Trenton High School graduate.

• Official website
• Trenton Public Schools