Treppo Grande (Friulian: Trep Grant) is a comune (municipality) in the Regional decentralization entity of Udine in the Italian region of Friuli-Venezia Giulia, located about 80 kilometres (50 mi) northwest of Trieste and about 15 kilometres (9 mi) northwest of Udine.

Treppo Grande borders the following municipalities: Buja, Cassacco, Colloredo di Monte Albano, Magnano in Riviera, Tricesimo.