Tyrone Armory is an historic National Guard armory located at Tyrone, Blair County, Pennsylvania. It was built between 1912 and 1918, and is an "I"-plan building built of Medina sandstone in the Late Gothic Revival style. The two-story front section houses administrative functions, and the rear is the former stable area. Between these sections is the drill hall, which has a hipped roof.

The armory was added to the National Register of Historic Places in 1989.