The Deputy Secretary of Veterans Affairs, in the United States government, is the chief operating officer of the United States Department of Veterans Affairs, responsible for a nationwide system of health care services, benefits programs, and national cemeteries for America's veterans and their dependents. The deputy secretary is the second-highest-ranking officer in the department and succeeds the Secretary in the event of his resignation, death, or otherwise inability to fulfill his duties.

The Deputy Secretary is appointed by the President and confirmed by the Senate. The position was created with the creation of the Department of Veterans Affairs in October 1988.

Tanya J. Bradsher is the current Deputy Secretary, replacing Donald Remy on a permanent basis, effective September 20, 2023.

List of deputy secretaries of veterans affairs

No.	Portrait	Name	Term of office		President(s) served under
			Start	End
1		Anthony Joseph Principi	March 17, 1989	September 26, 1992	George H. W. Bush
2		Hershel Wayne Gober	February 4, 1993	August 10, 2000	Bill Clinton
–		Edward A. "Ned" Powell, Jr. (acting)	August 10, 2000	January 20, 2001
3		Leo S. Mackay, Jr.	May 24, 2001	September 30, 2003	George W. Bush
4		Gordon H. Mansfield	January 22, 2004	January 20, 2009
5		W. Scott Gould	April 9, 2009	May 17, 2013	Barack Obama
6		Sloan D. Gibson	February 11, 2014	January 20, 2017
–		Gina Farrisee (acting)	January 20, 2017	February 25, 2017	Donald Trump
–		Scott Blackburn (acting)	February 26, 2017	August 9, 2017
7		Thomas G. Bowman	August 10, 2017	June 15, 2018
8		James Byrne	August 28, 2018	September 16, 2019
			September 16, 2019	February 3, 2020
–		Pamela J. Powers (acting)	April 2, 2020	January 20, 2021
–		Carolyn Clancy (acting)	January 20, 2021	July 19, 2021	Joe Biden
9		Donald Remy	July 19, 2021	April 1, 2023
–		Guy Kiyokawa (acting)	April 1, 2023	September 19, 2023
10		Tanya J. Bradsher	September 20, 2023	Incumbent