Centered around the Ohio River, the Upper Ohio Valley was historically a manufacturing center of the United States due to its strategic transportation location.
As of the census of 2000, there were 132,008 people, 54,491 households, and 37,250 families residing within the MSA. The racial makeup of the MSA was 94.50% White, 3.91% African American, 0.16% Native American, 0.34% Asian, 0.02% Pacific Islander, 0.19% from other races, and 0.88% from two or more races. Hispanic or Latino of any race were 0.61% of the population.
The median income for a household in the MSA was $32,531, and the median income for a family was $39,825. Males had a median income of $34,998 versus $19,729 for females. The per capita income for the MSA was $17,110.
^Manson, Steven; Schroeder, Jonathan; Van Ripper, David; Ruggles, Steven (2017). "IPUMS National Historical Geographic Information System: Version 12.0 [Database]". IPUMS NHGIS. Minneapolis: University of Minnesota. doi:10.18128/d050.v12.0.