The Urban Municipality of Novo Mesto (pronounced [ˈnɔːʋɔ ˈmeːstɔ]; Slovene: Mestna občina Novo mesto) is a municipality in southeastern Slovenia, close to the border with Croatia. The seat of the municipality is the city of Novo Mesto. The Municipality of Novo Mesto is part of the Southeast Slovenia Statistical Region. It borders Croatia on the Gorjanci Hills.

The total municipal area is 298.5 square kilometres (115.3 sq mi), located on a bend of the Krka River.

The municipality is divided into the local communities (Slovene: krajevne skupnosti) of Birčna Vas, Bršljin, Brusnice, Bučna Vas, Center, Dolž, Drska, Gabrje, Gotna Vas, Kandija–Grm, Karteljevo, Ločna–Mačkovec, Majde Šilc, Mali Slatnik, Mestne Njive, Otočec, Podgrad, Prečna, Regrča Vas, Šmihel, Stopiče, Uršna Sela, and Žabja Vas.

In addition to the municipal seat of Novo Mesto, the municipality also includes the following settlements:

In 1923, Kandija was annexed to Novo Mesto.

In 1979, the following settlements were annexed to Novo Mesto: Brod (at the time of the 1971 census, the settlement had 247 inhabitants), Bršljin (520), Cegelnica pri Novem Mestu (307), Dolenje Kamence (316), Gotna Vas (470), Groblje (34), Irča Vas (376), Jedinščica (132), Krka (141), Ločna (246), Mačkovec pod Trško Goro (192), Mala Bučna Vas (239), Muhaber (288), Potočna Vas (113), Ragovo (95), Regrča Vas (587), Šmihel pri Novem Mestu (504), Velika Bučna Vas (185), Velika Cikava (51), and Žabja Vas (761).

According to the census of 2002, the municipality has 40,925 inhabitants, 20,017 male and 20,908 female. The average age of the inhabitants is 39.58. There are a total of 13,796 households and 11,408 families. The Urban Municipality of Novo Mesto has a working-age population of 19,579, of whom 2,118 are unemployed. The average gross monthly wage in August 2003 was €1,099.27 (263,432 tolars) and the average net monthly wage was €687.90 (164,851 tolars). There are 1,725 students in the municipality.

Today, tourism is increasing in Slovenia, and Novo Mesto is feeling some of the effects of this. The Krka Valley is becoming a place for wine enthusiasts who take tours throughout the Lower Carniola region, tasting locally produced Cviček wine, which is produced by blending several different varieties of local wine.

Major industries include:

• REVOZ (ex Industrija motornih vozil), car manufacturing
• Adria Mobil, caravaning
• Krka (company), pharmaceuticals

• Krka Basketball Club
• Langenhagen – the twin city of Novo Mesto
• Novo Mesto Grammar School

• Media related to City Municipality of Novo Mesto at Wikimedia Commons
• Urban Municipality of Novo Mesto on Geopedia
• Novo Mesto, official municipal web page