Uryupinsk (Russian: Урю́пинск) is a town in Volgograd Oblast, Russia, located 340 kilometers (210 mi) northwest of Volgograd on the Khopyor River. Population: 41,590 (2010 Census); 41,960 (2002 Census); 42,954 (1989 Soviet census).

There are two theories of the historical background for the town's name. One is that it is from name of a Tartar prince Uryup, who got bogged down in a swamp near this location, during a fight with Yermak and got captured. Another is that it is from either the family name Uryupin or the word "урюпа" (uryupa). According to the 1866 Explanatory Dictionary of the Living Great Russian Language by Vladimir Dal, this archaic word means untidy person, which probably in this context characterizes not a person, but the swampy area.

The name of this town is known to many Russian people as a synonym for "backwater town". This usage became widespread after the popular Soviet film Destiny of a Man. The film was based on a short story by Mikhail Sholokhov, and Uryupinsk was the place of the action, shown as an inconspicuous provincial town.

Founded in the late 14th–early 15th century as Uryupin, it was a border outpost of the Principality of Ryazan, populated by Don Cossacks. Since 1857, it is the stanitsa Uryupinskaya and home of Pokrovskaya Fair, a center for trade on the southeastern side of the East European Plain. It was renamed Uryupinsk and granted town status in 1929.

According to the alphabetical list of settlements of the Donskoy Army region in 1915: 5,782 men and 6,316 women lived in the village, the land allotment of the village amounted to 25,354 tithes of land, the office of the district ataman, the district zemsky council, the district leader of the nobility, the postal and telegraph office, a real school, a women's gymnasium, a city school, a women's 4th grade a school, two two-class schools, two parish schools, a military craft school, a district hospital, a committee of the Russian Red Cross Society, a fire brigade, a commercial and industrial mutual credit society, the Ust-Medveditsky District Court, investigators of three sites, a notary, a prison and other officials and institutions

In 1921, the village was incorporated into the Tsaritsyn province. Since 1928, it has been the administrative center of the Uryupinsky district of the Khopersky district (abolished in 1930) The Lower Volga Region

It is assumed that it is listed in the historical List of Ruthenian Cities Far and Near under the name "Uryupesk" (Урюпеск).

Within the framework of administrative divisions, Uryupinsk serves as the administrative center of Uryupinsky District, even though it is not a part of it. As an administrative division, it is incorporated separately as the "town of oblast significance of Uryupinsk"—an administrative unit with the status equal to that of the districts. As a municipal division, the town of oblast significance of Uryupinsk is incorporated as Uryupinsk Urban Okrug.

Uryupinsk is an industrial center with heavy industries such as agricultural machinery (harvesting machines) and loading equipment (a large crane-making plant is located here). The city also contains factories of light industry production (such as knitted fabric, shoe fabric, and furniture fabric), paper production plant, and a packing plant.

Another major industry involving the outlying areas of the town is goat farming and goat leather production. Because of its mild southern climate, the region is a good area for agriculture, and there are many agricultural processing factories in the region, specializing mainly in beef, oil and butter production.

• Волгоградская областная Дума. Закон №139-ОД от 7 октября 1997 г. «Об административно-территориальном устройстве Волгоградской области», в ред. Закона №107-ОД от 10 июля 2015 г. «О внесении изменений в отдельные законодательные акты Волгоградской области в связи с приведением их в соответствие с Уставом Волгоградской области». Вступил в силу со дня официального опубликования. Опубликован: "Волгоградская правда", №207, 1 ноября 1997 г. (Volgograd Oblast Duma. Law #139-OD of October 7, 1997 On the Administrative-Territorial Structure of Volgograd Oblast, as amended by the Law #107-OD of July 10, 2015 On Amending Various Legislative Acts of Volgograd Oblast to Ensure Compliance with the Charter of Volgograd Oblast. Effective as of the day of the official publication.).
• Волгоградская областная Дума. Закон №1008-ОД от 21 февраля 2005 г. «Об установлении границ и наделении статусом города Урюпинска Волгоградской области». Вступил в силу со дня официального опубликования. Опубликован: "Волгоградская правда", №36, 2 марта 2005 г. (Volgograd Oblast Duma. Law #1008-OD of February 21, 2005 On Establishing the Borders and Granting the Status to the Town of Uryupinsk of Volgograd Oblast. Effective as of the day of the official publication.).
• Волгоградская областная Дума. Закон №1037-ОД от 30 марта 2005 г. «Об установлении границ и наделении статусом Урюпинского района и муниципальных образований в его составе», в ред. Закона №67-ОД от 4 июля 2013 г. «О внесении изменений в некоторые законодательные акты Волгоградской области по вопросам исключения из учётных данных отдельных населённых пунктов Волгоградской области». Вступил в силу со дня официального опубликования. Опубликован: "Волгоградская правда", №60, №147 (уточнение), 6 апреля 2005 г., 11 августа 2005 г. (Volgograd Oblast Duma. Law #1037-OD of March 30, 2005 On Establishing the Borders and Granting the Status to Uryupinsky District and the Municipal Formations Comprising It, as amended by the Law #67-OD of July 4, 2013 On Amending Various Legislative Acts of Volgograd Oblast Due to the Exclusion from the Registries of Several Inhabited Localities of Volgograd Oblast. Effective as of the day of the official publication.).