Vacqueyras (French pronunciation: [vakeʁas]; Occitan: Vacairaç) is a commune in the Vaucluse department in the Provence-Alpes-Côte d'Azur region in southeastern France.

Vacqueyras is also the name of an Appellation for a wine from the Côtes du Rhône.

Departmental Route 8 arrives at the north of the commune, then Departmental Route 7 traverses the commune on a north-south axis, forking to the southeast near Beaumes-de-Venise. Departmental route 52 then continues on to the south.

Departmental Route 233 leaves at the east near Peyre's Wood.

Containing many alternating little valleys of minimal depth and plains + hills to the east, (261 m to the Muse), the extremity is at the Dentelles de Montmirail.

The Dentelles de Montmirail are the furthest west of the Massif des Baronnies and constitute the first advance of the Alps into the Rhone Valley.

Rocky stones from the Late Jurassic (Tithonian) period with clay-limestone soil dominate the area.

The small stream Limade passes to the north of and flows into the Ouvèze, which passes to the west.

The Canal de Carpentras built in 1856, crosses the commune, and provides irrigation, thanks to a network of fillioles(small irrigation channels).

Mediterranean plants on the Dentelles de Montmirail compare to those from the Alpilles in many places. One can find aromatic plants (thyme, rosemary, fennel, lavender), Evergreen Oaks and Provençal White Pines (Aleppo Pines), etc.

Vines grow well on the hillsides and also on the stony flat ground, at higher levels.

Historical population

Year	Pop.	±% p.a.
1968	866	—
1975	816	−0.85%
1982	883	+1.13%
1990	943	+0.83%
1999	1,061	+1.32%
2007	1,060	−0.01%
2012	1,085	+0.47%
2017	1,308	+3.81%
Source: INSEE

• Dentelles de Montmirail
• Communes of the Vaucluse department
• Vacqueyras AOC
• Raimbaut de Vaqueiras