Van Nuys station is an Amtrak and Metrolink train station in the Van Nuys neighborhood of Los Angeles, California, close to the nighborhood of Panorama City. Amtrak's Pacific Surfliner from San Luis Obispo to San Diego, Amtrak's Coast Starlight from Los Angeles to Seattle, Washington, and Metrolink's Ventura County Line from Los Angeles Union Station to East Ventura stop here.

Van Nuys station is served by ten Amtrak Pacific Surfliner trains (five in each direction) every day and two Coast Starlight trains (one in each direction), with departures evenly spaced throughout the day. Twenty Metrolink Ventura County Line trains (ten in each direction) serve the station each weekday, running during peak hours in the peak direction of travel. On weekends, four Metrolink Ventura County Line trains (two in each direction) serve the station. Metrolink passengers also have access to all Pacific Surfliner trains through a codesharing arrangement with Amtrak.

The station when opened the first time in 1982 was called Panorama City and was served by the short-lived CalTrain service in 1982–83. In 1988, service was restored with the Amtrak San Diegan with the station renamed as Van Nuys, and Metrolink service began in 1992.

The diagonal railway across the San Fernando Valley was built in 1904 as a cutoff for the Southern Pacific Coast Line. At the time the main Van Nuys station was located further south on the Burbank branch, at the modern Van Nuys G Line station.

Panorama City station opened with the inauguration of CalTrain on October 18, 1982. The short-lived service ended on March 1, 1983. Amtrak service to Van Nuys (the former CalTrain station) began on June 26, 1988, when one San Diegan round trip was extended to Santa Barbara. Metrolink began Ventura County Line service with a stop at Van Nuys on October 26, 1992. A modern glass-and-concrete Van Nuys station building, funded by Caltrans, opened on December 18, 1995.

The station originally had a single side platform serving the southern track of the two-track Ventura Subdivision. A third track to the north is part of the Union Pacific Railroad Gemco Yard. In January 2018, Metrolink began construction of an island platform — which serves both main tracks — and a pedestrian underpass. Original plans called for a second side platform instead, but the island platform design had fewer impacts. The project was originally to be completed in late 2019, but was not officially finished until January 2020.

Van Nuys is expected to be expanded in the coming years to provide more connectivity through the Valley and the rest of Los Angeles County.

The Los Angeles County Metropolitan Transportation Authority East San Fernando Valley Light Rail Transit Project line runs adjacent to the station and the agency is planning a stop near Keswick Street to provide an interchange between systems. A new island platform in the median of Van Nuys Boulevard is expected to open for service in 2031. That line's maintenance and storage facility is additionally planned to be located nearby.

This is the northernmost station of the further planned Sepulveda Transit Corridor. As of 2020 new subway or aerial platforms are planned to be built at Van Nuys for the service.

Media related to Van Nuys station at Wikimedia Commons

• Van Nuys, CA – Amtrak
• Van Nuys, CA – Station history at Great American Stations (Amtrak)
• Van Nuys – Metrolink
• Van Nuys, CA – USA Rail Guide (TrainWeb)