Vignole (also Le Vignole) is an island in the Venetian Lagoon, northern Italy, with an area of 69.20 ha (171 acres). It is located north-east of Venice, between the islands of Sant'Erasmo and La Certosa.

Vignole consists of two islands which are connected by a bridge. As with neighbouring Sant'Erasmo, Vignole has a small population most of whom work in agriculture. The eastern part of the island is a military zone, housing facilities of the amphibious Lagunari Regiment "Serenissima". Two bridges connect the military zone to Sant'Andrea Island, the location of Forte di Sant'Andrea [it], a mid-16th century fortress.

Historically, the island was used by the ancient Romans and the Venetians as a vacation place. It directly faced the Adriatic Sea before accumulation of sand at Punta Sabbioni.

In the 7th century two tribunes from Torcello built a small church dedicated to St. John the Baptist and St. Christine. The few other points of interest include the small church of St. Eurosia, with a small bell tower.

The island is accessed on Actv waterbus line 13 (Fondamente Nove-Murano-Vignole-Lazzaretto Nuovo-Sant'Erasmo-Treporti). It is also served by a night service.

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  Part of the lagoon from the east. Vignole is in the centre, extending to the right. Venice is in the upper left.
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  St. Eurosia's church
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  Forte S Andrea