The Vikšrupis is a river of Kėdainiai district municipality, Kaunas County, central Lithuania. It flows for 16.9 kilometres (10.5 mi) and has a basin area of 30.4 km (11.7 sq mi). The river is a right tributary of the Šušvė.

It starts near Jakšiai village, then flows to the west through the Pernarava-Šaravai Forest. The lower course is designated as the Pavikšrupys Botanical Zoological Sanctuary.

The hydronym Vikšrupis is a compound noun which the first root vikšr- could mean either 'rush' (vikšris) or 'caterpillar' (vikšras) while the second root up- means 'river' (upė).