Wāṇa or Wanna (Pashto: واڼه, Wāṇə [ˈwɑɳə]; Urdu: وانا) is the largest town in the South Waziristan District of the Khyber Pakhtunkhwa province of Pakistan. It is the summer headquarters for the agency's administration, Tank located in the neighbouring Tank District being the winter headquarters.

Wanna is also one of the three subdivisions of South Waziristan along with Ladha and Sarwakai. The subdivision of Wanna is further divided into three tehsils: Wanna, Barmal, and Toi Khwla.

During the British Empire, beginning in the late 19th century, the British established a cantonment on the Wanna Plain which was used as a headquarters by the British forces in South Waziristan till the partition of India in 1947. During their rule, the Pashtun tribes of Waziristan - part of the Karlanri Tribal Confederation - gave the British much headache. In fact, the British, known then as the 'foreigners' , had to deal with a full-fledged insurgency in Waziristan in the 1930s. At one point during the 1930s, the British had up to 18,000 troops in and around Waziristan, with Wanna being used as the forward headquarters and airbase.

During 1989, the city underwent a striking increase in Malaria with a village Azam Warsak suffering the most.

Wanna has been involved in the War on Terror due to the Al-Qaeda members affiliated with the Taliban-aligned Ahmadzai Waziris of the Wanna Plain. The Pakistan Armed forces have been conducted several armed operations against these Al-Qaeda members since August 2003 off and on with limited success. Perhaps the town's most violent incident in the War on Terror was the Battle of Wanna which took place in March 2004 and included fighters from the Pakistani Army against Al-Qaeda and Taliban forces. More than 100 armed personnel were killed during the week of the fighting.

Inhabitants of Wanna are Muslim Pashtuns, primarily Ahmedzai Waziris from the Wazir tribe but other Pashtun tribes such as Mahsud and Bettani also live in the surroundings of Wanna.

• Waziristan and Mughal empire
• Nehru in Waziristan
• Sketch map of Waziristan
• Mehsuds and Wazirs, the King-makers in a game of thrones
• Lawrence of Arabia in Waziristan