Warren House and Warren's Store is a historic house and store and national historic district located at Prospect Hill, Caswell County, North Carolina. The house was built about 1858, and is a two-story, three-bay, Greek Revival style frame dwelling. It is set on a brick foundation and has a low hipped roof. The front facade features a two-story, three-bay, pedimented porch. Warren's Store and Post Office is located across from the house and is a two-story rectangular brick building of vernacular Greek Revival temple-form design. Also on the property is the contributing kitchen building.

It was added to the National Register of Historic Places in 1973.