Weser-Aue is a Samtgemeinde ("collective municipality") in the district of Nienburg, in Lower Saxony, Germany. Its seat is in the village Marklohe. It was established on 1 November 2021 by the merger of the former Samtgemeinden Marklohe and Liebenau.

The Samtgemeinde Weser-Aue consists of the following municipalities:

1. Balge
2. Binnen
3. Liebenau
4. Marklohe
5. Pennigsehl
6. Wietzen