Wheeling station is a U.S. historic train station located at Wheeling, Ohio County, West Virginia. It was built in 1907–1908, and is a four-story, rectangular brick and limestone building in the Beaux-Arts-style. It measures 250 feet long by 89 feet, 6 inches, deep. It features mansard roofs, built of concrete and covered with Spanish tile painted pink. Passenger service ceased in 1961. The building was remodeled in 1976 to house the West Virginia Northern Community College.

It was listed on the National Register of Historic Places in 1996 as the Wheeling Baltimore and Ohio Railroad Passenger Station.

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  B & O Passenger Station at Wheeling (ca. 1913)

• List of historic sites in Ohio County, West Virginia
• List of Registered Historic Places in West Virginia

Preceding station	Baltimore and Ohio Railroad			Following station
Benwood Junction toward Cincinnati		Cincinnati – Pittsburgh		Elm Grove toward Pittsburgh
Benwood Junction toward Cleveland		Cleveland – Akron – Wheeling		Terminus
Benwood Junction toward Kenova		Kenova – Wheeling
Terminus		Wheeling – Grafton		Benwood Junction toward Grafton