Wielkie Wyręby [ˈvjɛlkʲɛ vɨˈrɛmbɨ] is a village in the administrative district of Gmina Gniew, within Tczew County, Pomeranian Voivodeship, in northern Poland. It lies approximately 11 kilometres (7 mi) south-west of Gniew, 36 km (22 mi) south of Tczew, and 65 km (40 mi) south of the regional capital Gdańsk.

For details of the history of the region, see History of Pomerania.