Wiercień Duży [ˈvjɛrt͡ɕɛɲ ˈduʐɨ] is a village in the administrative district of Gmina Siemiatycze, within Siemiatycze County, Podlaskie Voivodeship, in north-eastern Poland. It lies approximately 9 kilometres (6 mi) north of Siemiatycze and 72 km (45 mi) south of the regional capital Białystok.

In 2008 the village had a population of 120.