State Trunk Highway 50 (often called Highway 50, STH-50 or WIS 50) is a 44.43-mile (71.50 km) state highway in Walworth and Kenosha counties in Wisconsin, United States, that runs from Wisconsin Highway 11 (WIS 11) in Delavan east to Wisconsin Highway 32 (WIS 32) in Kenosha. The highway is maintained by the Wisconsin Department of Transportation.

Highway 50 begins at an intersection with Highway 11 in Delavan. The highway crosses Wisconsin and Southern Railroad tracks and heads east to a junction with Interstate 43 at Exit 21. Highway 50 continues southeast out of Delavan, crossing Delavan Lake at the city's eastern border, and intersects Highway 67 north of Williams Bay. Highway 50 heads east from this intersection toward Lake Geneva, where it intersects Highway 120. Shortly after this intersection, Highway 50 meets U.S. Route 12 at Exit 330. The highway continues eastward from Lake Geneva to the border of Kenosha County.

After entering Kenosha County, Highway 50 passes the community of Slades Corners before meeting Highway 83 in New Munster. The two highways become concurrent and continue eastward until they meet Highway 75 in Paddock Lake. At this junction, Highway 83 turns southward, and Highway 50 continues eastward toward Bristol. The highway intersects U.S. Route 45 in Bristol and continues east to meet Interstate 94 and U.S. Route 41 at Exit 344. Highway 50 then straddles the border of Kenosha and Pleasant Prairie, meeting Highway 31 along this border. The highway then turns northeast and passes through Kenosha before terminating at Highway 32.

Highway 50 was designated in 1917, and signage for the highway was posted in 1918. The highway has changed little since and still follows its original route for most of its length. The route of Highway 50 through Kenosha changed in 1997; the highway moved from 75th Street to a more northerly alignment along Roosevelt Road and 63rd Street.

County	Location	mi	km	Destinations	Notes
Walworth	Delavan	0.0	0.0	WIS 11 – Elkhorn, Janesville
		1.4	2.3	I-43 – Milwaukee, Beloit
	Williams Bay	6.1	9.8	WIS 67 – Elkhorn, Williams Bay
	Lake Geneva	13.2	21.2	WIS 120 south	Western end of WIS 120 concurrency
		13.5	21.7	US 12 / WIS 120 north – Madison, Chicago	Eastern end of WIS 120 concurrency
Kenosha	New Munster	23.6	38.0	WIS 83 north – Burlington	Western end of WIS 83 concurrency
	Paddock Lake	29.1	46.8	WIS 75 north / WIS 83 south – Burlington, Salem	Eastern end of WIS 83 concurrency
	Village of Bristol	32.6	52.5	US 45 – Union Grove, Bristol
	Kenosha–Pleasant Prairie city/village line	37.4	60.2	I-41 / I-94 / US 41 – Milwaukee, Chicago
	Kenosha	40.7	65.5	WIS 31 – Racine, Waukegan
		44.4	71.5	WIS 32 / LMCT (Sheridan Rd)
1.000 mi = 1.609 km; 1.000 km = 0.621 mi       Concurrency terminus

• U.S. Roads portal

• Media related to Wisconsin Highway 50 at Wikimedia Commons