Wyckoffs Mills is an unincorporated community located along the border of Cranbury and Monroe townships in Middlesex County, in the U.S. state of New Jersey. Located at the intersection of Wyckoff Mills Road and Wyckoffs Mills Road, the area only contains lots containing residential structures; the remainder of the land is made up of farmland and wetlands. The Millstone River flows to the south of the settlement and a 500-kilovolt transmission line crosses the farmland to the north and south.