The Yentna River (Dena'ina: Yentnu) is a river in South Central Alaska, formed by its East Fork and West Fork at 62°16′50″N 151°46′26″W / 62.28056°N 151.77389°W / 62.28056; -151.77389, flows South-East to Susitna River, 30 miles (48 km) North-West of Anchorage, Alaska, at Cook Inlet Low.

Tanaina Indian name reported by Spurr (1900, p. 46), United States Geological Survey. "Sometimes called Johnson River after the first white man to ascend it."

It begins in the Mount Dall and Yentna glacier systems and flows southeast to the Susitna River 2 miles (3.2 km) north of Susitna. The river system (including upstream tributaries) is about 100 miles (160 km) long.

From mouth to source:

• Kahiltna River 61°51′11″N 150°46′46″W / 61.85306°N 150.77944°W / 61.85306; -150.77944 (Kahiltna River), Elevation: 75 feet (23 m)
• Bottle Creek (Yentna River) 61°57′49″N 151°4′44″W / 61.96361°N 151.07889°W / 61.96361; -151.07889 (Bottle Creek (Yentna River)), Elevation: 125 feet (38 m)
• Skwentna River 61°59′8″N 151°8′23″W / 61.98556°N 151.13972°W / 61.98556; -151.13972 (Skwentna River), Elevation: 125 feet (38 m)
• East Fork Yentna River 62°16′49″N 151°46′26″W / 62.28028°N 151.77389°W / 62.28028; -151.77389 (East Fork Yentna River), Elevation: 200 feet (61 m)
• West Fork Yentna River 62°16′49″N 151°46′26″W / 62.28028°N 151.77389°W / 62.28028; -151.77389 (East Fork Yentna River), Elevation: 200 feet (61 m)

Lake Creek just about 8 miles down river from Bottle Creek. Major fishing area: kings, reds, silvers. Winter sports, hunting. Moose Creek, Indian Creek, Fish lakes Creek, Hewitt Creek, Malone's Slough, Donkey Creek, Johnson Creek, Clearwater Creek, Rich Creek, Flag Creek, Delta Creek, Fourth of July Creek, & Kichatna River round out the rest of the main Yentna River Tributaries.

List of rivers of Alaska