Ypoá National Park (Spanish: Parque Nacional Ypoá), encompassing Ypoá Lake, is a protected area in Paraguay. It was created by decree by Executive State order No. 43,681, dated 29 May 1992. One of its objectives is the preservation and protection of the wetlands of Ñeembucú and of the biodiversity of ecosystems and characteristic species. It also protects natural landscapes of exceptional beauty.

The park lies between the departments of Paraguarí, Central and Ñeembucú, and a portion of the districts of Caapucú, Villa Oliva, San Roque González de Santa Cruz and Quiíndy. It has a total area of 1,000 km (390 sq mi) and is 150 km from Asunción.

The occupation of the area is really old. An example of that is on the eastern side of the lake with lines of mollusc shell middens, predominantly of Ampllaria and Diplodon species, and sites of campfires made by former inhabitants.

The vegetation in this area is related directly with the eco-region of Ñeembucú, where can be found species such as espinillo, palo negro, ingá, lapacho, yvyra ovi, among others. Also pacurí and al yuasy-iy can be found. The riparian and aquatic vegetation is formed by camalote, caña brava, pirí, among others.

Its fauna is varied with species such as the toucanos, ñandú, suruku'a, inambú, mbiguá, chahá, taguatí, caburé, carpincho, rabbits, monkeys, guazutí, stags, agurá, crocodiles, teja, snakes and others.

The park has been designated an Important Bird Area (IBA) by BirdLife International because it supports significant populations of strange-tailed tyrants, ochre-breasted pipits and chestnut seedeaters.

The park was listed as a "Wetland of International Importance" under the Ramsar Convention on 7 June 1995.

• List of national parks of Paraguay