Zacisze [zaˈt͡ɕiʂɛ] is a settlement in the administrative district of Gmina Borek Wielkopolski, within Gostyń County, Greater Poland Voivodeship, in west-central Poland. It lies approximately 6 kilometres (4 mi) south-west of Borek Wielkopolski, 14 km (9 mi) east of Gostyń, and 62 km (39 mi) south of the regional capital Poznań.