Zakrzewo Wielkie [zaˈkʂɛvɔ ˈvjɛlkʲɛ] is a village in the administrative district of Gmina Grudusk, within Ciechanów County, Masovian Voivodeship, in east-central Poland. It lies approximately 7 kilometres (4 mi) south-west of Grudusk, 18 km (11 mi) north of Ciechanów, and 94 km (58 mi) north of Warsaw.