Zhizdrinsky District (Russian: Жиздринский райо́н) is an administrative and municipal district (raion), one of the twenty-four in Kaluga Oblast, Russia. It is located in the south of the oblast. The area of the district is 1,250 square kilometers (480 sq mi). Its administrative center is the town of Zhizdra. Population: 10,089 (2021 Census); 10,593 (2010 Russian census); 11,725 (2002 Census); 13,737 (1989 Soviet census). The population of Zhizdra accounts for 55.0% of the district's total population.