Zotzenheim is an Ortsgemeinde – a municipality belonging to a Verbandsgemeinde, a kind of collective municipality – in the Mainz-Bingen district in Rhineland-Palatinate, Germany.

The municipality lies in Rhenish Hesse. It belongs to the Verbandsgemeinde of Sprendlingen-Gensingen, whose seat is in Sprendlingen.

On Kreuznacher Straße is found a cinder team handball court and a clubhouse. HSG Zotzenheim/St. Johann/Sprendlingen is a successful team handball club that grew out of TV Zotzenheim 1901 (gymnastic club) and has already played several times in the third handball league.

• On 1 May near the Napoleonshöhe mountain, or Gipfel des Horns, or in the local speech also “Hörnchen” (“Little Horn”), the so-called Fire Brigade Festival (Feuerwehrfest) takes place.
• In May on the weekend at Ascension Day, a folk festival for the region and beyond is held. In 2006, among others, the bands Paddy Goes To Holyhead, Dhalia's Lane, Galahad and WirrWarr appeared.
• On the second weekend in July, a fair is held in Zotzenheim with a wine tent, a few stands and a handball tournament.
• Zotzenheim is especially well known for the ZDF (Zotzenheimer Dorf-Fassenacht – the Carnival). Each year there are four “sessions” at the village community centre.

Zotzenheim is home to five major wineries:

• Weingut Werner Pitthan
• Weingut Philipp Schnell
• Weingut Siebenhof
• Weingut Scheffer
• Weingut Saulheimer

There are also several smaller wineries and those who do it as a hobby.

In the industrial park outside Zotzenheim on the street Am neuen Graben, several small businesses have set up shop, among them the Sand Barth shipping company.

• Municipality’s official webpage (in German)
• Verbandsgemeinde of Sprendlingen-Gensingen (in German)