Zürich Affoltern railway station (‹See Tfd›German: Bahnhof Zürich Affoltern) is a railway station in the Affoltern quarter of the Swiss city of Zürich. The station is located on the Wettingen–Effretikon railway line (Furttal line).

The station is not to be confused with Affoltern am Albis railway station, which is located in Affoltern am Albis (Säuliamt), canton of Zürich.

In 2010, the station was rebuilt with the introduction of a convenience store and parking for 130 bicycles. The store is open 365 days a year from dawn to dusk and is part of the Migrolino chain owned the Migros company. The former station building (Alter Bahnhof) is situated to the west of the current location, on the opposite side of Zehntenhausstrasse.

The station is served by line S6 of the Zürich S-Bahn, along with bus routes 37, 61 and 62 of the Verkehrsbetriebe Zürich (VBZ). Some trains of the peak-hour service S21 also call at Zürich Affoltern station. On weekends, there is a nighttime S-Bahn service (SN6) offered by ZVV.

Summary of all S-Bahn services:

• Zürich S-Bahn:
  • S6: half-hourly service to Baden, and to Uetikon via Zürich HB.
  • S21: half-hourly service to Regensdorf-Watt, and to Zürich HB via Zürich Hardbrücke (limited service at Zürich Affoltern station).
  • Nighttime S-Bahn (only during weekends):
    • SN6: hourly service to Würenlos, and to Winterthur via Zürich Stadelhofen.

• Media related to Zürich Affoltern railway station at Wikimedia Commons
• Zürich Affoltern railway station – SBB