The 46th Separate Airmobile Brigade (Ukrainian: 46-та окрема аеромобільна бригада; 46 ОАеМБр; Military Unit Number A4350) is a brigade of the Ukrainian Air Assault Forces formed in 2016, based in Poltava.

The United Kingdom offered the Ukrainian government training on British soil for Ukrainian recruits, and the 46th Air Assault Brigade was one of the selected brigades. Fresh Western supplies, like as Wolfhound MRAPs and Husky TSV tactical vehicles, were also delivered to the brigade. The Brigade was converted from a heavy assault brigade to a light assault brigade. The 46th Airmobile Brigade took part in the Kherson operation after arriving from the United Kingdom. The Brigade no longer uses equipment built in the Soviet Union or Ukraine, such as BTR-3s, BMP-1s, or T-80s.

The Brigade from Poltava was dubbed the 46th Airmobile Brigade. The unit also got a new emblem.

The unit was an integral part of the defense in Bakhmut and in Soledar, both of which have been the site of some of the most intense fighting in the war.

On March 13, 2023, the Washington Post published a news report after interviewing the then Commander of the 46th Airmobile Brigade Anatolii "Kupol" Kozel stating that Ukraine was short of skilled troops, munitions and was sustaining high losses as pessimism grew. In his interview, Anatolii "Kupol" Kozel admitted to getting 100 new soldiers every week who were poorly trained and that most of these soldiers would flee or refuse to fire their weapons as they were afraid of the sound of the shots. Anatolii "Kupol" Kozel was demoted to deputy commander after his interview and in response resigned from the Armed Forces of Ukraine. In the aftermath, a video of soldiers from the 46th Airmobile Brigade surfaced on various telegram channels protesting the demotion of Anatolii "Kupol" Kozel.

During the 2023 Ukrainian Counteroffensive the brigade was involved in Southern Ukraine campaign in the Zaporizhzhia Oblast Orikhiv direction.

In December 2023, the brigade's Garuda drone team began operating near Mar'inka, Donetsk Oblast. It is believed the entire brigade has moved to that direction, though this is unconfirmed.

On 20 September, the brigade claimed to have repulsed two Russian assaults, totaling 98 vehicles, over a week in defending Kurakhove. They claimed to have damaged or destroyed 44 of the attacking vehicles using tanks, artillery and thermite drones, while allegedly killing 72 Russians on the 20th alone.

The brigade claimed to have destroyed 100 armored vehicles, including tanks, in the Kurakhove area in October 2024.

As of 2023 the brigade's structure is as follows:

• 46th Air Assault Brigade, Poltava
  • Headquarters & Headquarters Company
  • 1st Airmobile Battalion
  • 2nd Airmobile Battalion
  • 3rd Airmobile Battalion
    • Anti-tank Company
    • Artillery Company
    • UAV Unit
  • 4th Airmobile Battalion
  • Artillery Group (equipped with 2S1 and BM-21 Grad)
    • Self-propelled howitzer-artillery division (2S1)
    • Howitzer Artillery Division (D-30)
    • Anti-tank battery
  • Anti-Aircraft Defense Battalion (equipped with Shilka)
  • Reconnaissance and Strike UAV Company "Garuda"
  • Support units (including engineers, communication, medics, and material support)