Bignona department (French: Département de Bignona) is one of the three departments in the Ziguinchor region of Senegal.

Within the department are three urban communes: Bignona, Thionck Essyl and Diouloulou.

The rest of the department is divided administratively into four arrondissements made up of rural districts (communautés rurales):

• Kataba Arrondissement (renamed from Diouloulou in 2008, when Diouloulou became a commune)
  • Kataba
  • Djinaky
  • Kafoutine
• Sindian Arrondissement:
  • Djibidione
  • Oulampane
  • Sindian [fr]
  • Suelle [fr]
• Tendouck Arrondissement:
  • Balinghor
  • Diégoune [fr]
  • Kartiack [fr]
  • Mangagoulack [fr]
  • Mlomp
• Tenghory Arrondissement:
  • Coubalan
  • Niamone [fr]
  • Ouonck
  • Tenghory [fr]

• Mausoleum of Ahoune Sané, Koundioughor, Sindian Arrondissement
• 100 year old Sindian Fromager (Kapok) tree, a place of worship for the rites of initiation
• Bakolon Badji site at Niankite, a place of worship for the rites of initiation
• Sweetwater wells at Kafountine, Arrondissement of Kataba
• Palm Baobab of Baligname
• Nankoray termite colony at Djilondine, place of worship for the animist priestesses

12°49′48″N 16°14′24″W / 12.830000°N 16.24°W / 12.830000; -16.24