The Church of the Annunciation of Our Lady of the Newarke in Leicester, was a collegiate church founded by Henry of Grosmont, 1st Duke of Lancaster, in 1353. The name "Newarke" is a translation of the Latin "novum opus" i.e. "new work" and was used to distinguish the church from the older collegiate church of Leicester Castle, the Church of St Mary de Castro. Duke Henry enlarged his father's hospital foundation in the southern extension to the castle bailey and built the new church to house a holy relic, part of the Crown of Thorns given him by John II of France. The church became a place of pilgrimage. Leland visited it around 1540, shortly before its destruction during the Suppression of the Chantries. He described the church as "not very great...but exceeding fair."

The Newarke Church is dedicated to the Annunciation of the Blessed Virgin Mary, a significant event in Christian theology marking the announcement of the birth of Jesus Christ. Its architecture reflects the styles prevalent during the medieval period, with features that have evolved over time.

Today, the church continues to be an active place of worship and a site of historical interest, attracting visitors interested in its architecture, history, and religious significance.

The church became an important burial place of notable members of the Lancastrian dynasty. Those buried here included:

• Henry, 3rd Earl of Lancaster
• Henry of Grosmont, 1st Duke of Lancaster — son of the above, grandfather of Henry IV of England.
• Constance of Castile, Duchess of Lancaster — second wife of John of Gaunt, daughter of Peter of Castile.
• Mary de Bohun — first wife of Henry IV, who died before he took the throne. She was the mother of Henry V of England.
• Mary Hervey, a member of John of Gaunt's household, who died c.1408, and whose alabaster tomb effigy was moved across the road to the chapel of the Trinity Hospital, where it still stands.

Early sources (the Frowyk Chronicle and the Ballad of Bosworth Field) strongly suggest that the church was where the naked corpse of Richard III of England was displayed after his death at Bosworth Field and prior to his burial in the Greyfriars priory.

Only two arches survive from the original building, preserved in situ under what is now the Hawthorn Building of De Montfort University, where the public can see them in what is now the university's heritage centre.