Czarkówka Duża [t͡ʂarˈkufka ˈduʐa] is a village in the administrative district of Gmina Perlejewo, within Siemiatycze County, Podlaskie Voivodeship, in north-eastern Poland. It lies approximately 3 kilometres (2 mi) north-east of Perlejewo, 25 km (16 mi) north-west of Siemiatycze, and 71 km (44 mi) south-west of the regional capital Białystok.