The fifth federal electoral district of Chiapas (Distrito electoral federal 05 de Chiapas) is one of the 300 electoral districts into which Mexico is divided for elections to the federal Chamber of Deputies and one of 13 such districts in the state of Chiapas.

It elects one deputy to the lower house of Congress for each three-year legislative period by means of the first-past-the-post system. Votes cast in the district also count towards the calculation of proportional representation ("plurinominal") deputies elected from the third region.

Under the 2022 districting plan, which will be used for the 2024, 2027 and 2030 federal elections, Chiapas's fifth district covers five municipalities in the central region of the state:

• Chamula, San Cristóbal de las Casas, San Juan Cancuc, Tenejapa and Zinacantán.

The district's head town (cabecera distrital), where results from individual polling stations are gathered together and collated, is the city of San Cristóbal de Las Casas.

With Indigenous and Afrodescendent inhabitants accounting for over 69% of its population, it is officially classified by the National Electoral Institute (INE) as an indigenous district.

2017–2022

Between 2017 and 2022, in addition to the five it comprises in the 2022 plan, the district also covered the municipality of San Lucas. The head town was at San Cristóbal de Las Casas.

2005–2017

In 2005–2017, the fifth district was located in the Chiapas Highlands north-western portion of the state and covered the municipalities of Amatenango del Valle, Chamula, Huixtán, Mitontic, San Cristóbal de Las Casas, Tenejapa, Teopisca and Zinacantán. The head town was at San Cristóbal de Las Casas.

1996–2005

Between 1996 and 2005, the fifth district had a slightly different configuration. It covered the following municipalities:

• Chamula, Huixtan, Mitontic, San Cristóbal de Las Casas, Tenejapa and Zinacantán, which remained part of the 2005–2017 composition, plus:
• Chalchihuitán, Chenalhó, Larráinzar and Pantelhó.

1978–1996

The districting scheme in force from 1978 to 1996 was the result of the 1977 electoral reforms, which increased the number of single-member seats in the Chamber of Deputies from 196 to 300. Under that plan, Chiapas's seat allocation rose from six to nine. The fifth district had its head town at Tapachula and it covered eight municipalities.

National parties
Current
	PAN
	PRI
	PT
	PVEM
	MC
	Morena
Defunct or local only
	PLM
	PNR
	PRM
	PP
	PPS
	PARM
	PFCRN
	Convergencia
	PANAL
	PSD
	PES
	PRD

Fifth federal electoral district of Chiapas

Election	Deputy	Party	Term	Legislature
1976	Gonzalo Esponda Zebadúa		1976–1979	50th Congress
1979	Jaime Coutiño Esquinca		1979–1982	51st Congress
1982	Faustino Roos Mazo		1982–1985	52nd Congress
1985	Antonio Melgar Aranda		1985–1988	53rd Congress
1988	César Ricardo Naumann Escobar		1988–1991	54th Congress
1991	José Antonio Aguilar Bodegas		1991–1994	55th Congress
1994	Hildiberto Ochoa Samayos		1994–1997	56th Congress
1997	Gilberto Velasco Rodríguez		1997–2000	57th Congress
2000	Nicolás Lorenzo Álvarez Martínez		2000–2003	58th Congress
2003	Florencio Collazo Gómez		2003–2006	59th Congress
2006	Jorge Mario Lescieur Talavera		2006–2009	60th Congress
2009	Sergio Lobato García		2009–2012	61st Congress
2012	Luis Gómez Gómez		2012–2015	62nd Congress
2015	María Soledad Sandoval Martínez		2015–2018	63rd Congress
2018	Clementina Marta Dekker Gómez		2018–2021	64th Congress
2021	Yeimi Aguilar Cifuentes		2021–2024	65th Congress
2024	Emilio Ramón Ramírez Guzmán		2024–2027	66th Congress

16°44′N 92°38′W / 16.733°N 92.633°W / 16.733; -92.633