J. P. Rizal Avenue, also known as J. P. Rizal Street, is a major local avenue in Makati and Taguig, Metro Manila, Philippines. It is a contour collector road on the south bank of the Pasig River that runs east–west from Pateros Bridge at the Taguig–Pateros boundary to its intersection with Zobel Roxas, Delpan, and Tejeron Streets at the Makati–Manila boundary. It is a component of Radial Road 4 (R-4). The avenue was named after the Philippines' national hero, Dr. José P. Rizal.

J. P. Rizal extends past Circumferential Road 5 into East Rembo, Comembo, and the municipality of Pateros as J. P. Rizal Avenue Extension. West of Zobel Roxas, it continues as Tejeron Street, ending at Pedro Gil Street. The eastern section and extension between Guadalupe Nuevo and Pateros was formerly called Guadalupe–Pateros Road, and its section from Lawton Avenue eastwards forms part of McKinley–Pateros Road.

The road starts at Pateros Bridge, which connects Taguig and Pateros, as a continuation of Gen. B. Morcilla Street past the Taguig River. It meanders through the residential communities of barangays Comembo, West Rembo, East Rembo, and Cembo. The road continues past Kalayaan Avenue. The Circumferential Road 5 (C-5) then crosses above the avenue; one cannot go into C-5 directly from J.P. Rizal Avenue except when using Kalayaan Avenue as a conduit. It intersects with Lawton Avenue just past the University of Makati campus, which connects it to Bonifacio Global City nearby. The avenue enters Makati at Guadalupe Nuevo as it crosses the San Jose Creek past the Guadalupe ferry terminal.

The Embo barangays of Comembo, Cembo, West Rembo, and East Rembo were part of Makati until October 2023 when the said barangays became part of Taguig.

Crossing under the Guadalupe Bridge of Epifanio de los Santos Avenue (EDSA), the road runs through Guadalupe Viejo and Rockwell Center. West of Estrella Street, it enters the Makati Población area, passing through the Makati Poblacion Park before coming to an intersection with Makati Avenue. The road gradually pulls away from the river, continuing on a straight path to Chino Roces Avenue and A.P. Reyes Avenue in barangays Olympia and Tejeros. The section from Makati Avenue then carries one-way westbound traffic, especially during daytime and rush hours up to Pasong Tirad. Located in this section are Makati City Hall and Circuit Makati, formerly the site of Santa Ana Race Track. The avenue then curves northwest past Pasong Tirad before coming to its western terminus at Zobel Roxas and Delpan Streets at the city's border with Manila, continuing as Tejeron Street.

The road is the old main road of Makati, once a municipality of the Province of Manila and later of Rizal. It also traversed what was previously part of Pateros. The first Municipal Building of Makati, the Presidencia, was also built along the road in 1918 at Plaza Trece de Agosto; it is now occupied today by the Museo ng Makati. The road was historically part of the Manila East Road and Calle Tejeron. Its segment from Malapad-na-bato (now East Rembo, the present-day location of Napindan Hydraulic Control System) westwards was also part of Route 21 or Highway 21 that linked Manila to Calamba, Laguna by circumscribing Laguna de Bay through Rizal, especially during the American colonial era.

Province	City/Municipality	km	mi	Destinations	Notes
Taguig – Pateros boundary				Pateros bridge over Taguig River (Eastern Terminus, continues east as B. Morcilla Street)
Taguig				Sampaguita Street / Anahaw Street	Traffic light intersection.
				Kalayaan Avenue	Traffic light intersection.
				Lawton Avenue	Traffic light intersection.
Makati				Sgt. Fabian Yabut Circle
				AH 26 (26) (EDSA) – Mandaluyong, Quezon City	Guadalupe interchange, traffic light intersection.
				AH 26 (26) (EDSA) – Pasay	Guadalupe interchange, traffic light intersection.
				Gonzales, Trinidad, Carballo, Progreso Streets
				Estrella Street
				Makati Avenue	Traffic light intersection; road becomes one-way westbound.
				E. Zobel Street	One-way road, no right turn allowed from westbound.
				F. Zobel Street	One-way road towards Makati City Hall
				Nicanor Garcia Street / Antipolo Street	Traffic light intersection.
				Pateros, Taguig Streets
				South Avenue/Taliba Street	Traffic light intersection; one-way road.
				Zapote Street	Traffic light intersection; one-way road.
				Chino Roces Avenue / A.P. Reyes Avenue	No crossing on J.P. Rizal westbound.
				Pasong Tirad Street	One-way road, J.P. Rizal becomes a two-way road.
				Zobel Roxas Street / Del Pan Street	Western terminus, continues to Manila as Tejeron Street.
1.000 mi = 1.609 km; 1.000 km = 0.621 mi       Incomplete access

• Casa Hacienda Park
• Circuit Makati (via Taliba and Zapote Streets)
  • Ayala Malls Circuit
  • Samsung Performing Arts Theater
• Guadalupe Linear Park
• Guadalupe Viejo Cloverleaf Park
• Holy Cross Parish Makati
• Kennely Ann L. Binay Park (Guadalupe Nuevo Cloverleaf Park)
• Makati Aqua Sports Arena
• Makati City Hall
• Makati Park and Garden
• Museo ng Makati
• Olympia Market
• Poblacion Park
• Poblacion Sports Complex
• Puregold Makati
• Rockwell Center
  • Nestle Philippines Inc.
  • Power Plant Mall
  • Proscenium
• University of Makati

• Pasig River Expressway

14°34′26″N 121°0′42″E / 14.57389°N 121.01167°E / 14.57389; 121.01167