St. John Paul II Catholic High School is a private, coeducational, Catholic high school in Tallahassee, Florida. It is a diocesan school of the Roman Catholic Diocese of Pensacola-Tallahassee and accredited by the Southern Association of Colleges and Schools.

SJPII, the first Catholic high school to be founded in Tallahassee, opened in 2001. It graduated its first class in 2004, with the first charter class graduating the next year, in 2005.

The St. John Paul II campus initially had a gymnasium, chapel, main building, soccer field, and baseball field. A softball field was added in 2013 and opened for the 2014 season. The school has plans for future expansion.

The school teaches several Advanced Placement Courses including:

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The school also has a wide range of clubs, among them an Automotive Club, Aerospace Engineering club, and Literary club.

SJPII has an active drama department, a chorus that competes statewide in choral competitions, and a creative arts department that has competed in art competitions and exhibited at various Tallahassee museums and shows. St. John Paul II puts on an annual arts and music festival known as SouthWoodStock featuring student and outside artists and musicians.

St. John Paul II High School's mascot is Pep the Panther, and their colors are Blue and Gold. SJPII has eight boys' athletic teams and nine girls' teams.

St. John Paul II School hosts the District volleyball, basketball and baseball events.

• Terrion Arnold, former college football cornerback for the Alabama Crimson Tide and current cornerback for the Detroit Lions.

• St. John Paul II Catholic High School