Kentucky Route 480 (KY 480) is a 13.481-mile-long (21.696 km) state highway in Kentucky that runs from Kentucky Route 61 in southern Shepherdsville to Kentucky Route 523 in rural Nelson County southeast of Mt. Washington via Cedar Grove.

County	Location	mi	km	Destinations	Notes
Bullitt	Shepherdsville	0.000	0.000	KY 61 (Preston Highway)	Western terminus
		0.075	0.121	KY 2237 north (Old Preston Highway South)	Southern terminus of KY 2237
		0.589	0.948	KY 480C west	Eastern terminus of KY 480C
		0.823	1.324	Sparrow Drive (KY 6317 north)	Southern terminus of KY 6317
		0.919– 1.058	1.479– 1.703	I-65 – Nashville, Louisville	I-65 exit 116
		1.164	1.873	Buffalo Run Road (KY 6318 west)	Eastern terminus; eastbound access and entrance only
	​	3.292	5.298	KY 1442 east (Ridge Road)	Western terminus of KY 1442
	​	5.141	8.274	KY 1604 south (Deatsville Road)	Northern terminus of KY 1604
	​	8.403	13.523	KY 1442 west (Clarks Lane)	Eastern terminus of KY 1442
Nelson	​	13.257	21.335	US 31E / US 150
	​	13.481	21.696	KY 523 (Colonel Cox Road South)	Eastern terminus
1.000 mi = 1.609 km; 1.000 km = 0.621 mi       Incomplete access

Kentucky Route 480C
Location	Shepherdsville
Length	0.916 mi (1,474 m)

Kentucky Route 480C (KY 480C) is a 0.916-mile-long (1.474 km) state highway in Shepherdsville, Bullitt County, Kentucky that serves as a connector route for Kentucky Route 480. It runs from Kentucky Route 61 to Kentucky Route 480 in southern Shepherdsville.

The entire route is in Shepherdsville, Bullitt County.

mi	km	Destinations	Notes
0.000	0.000	KY 61 (Preston Highway)	Western terminus
0.481	0.774	KY 2237 south (Old Preston Highway South)	Northern terminus of KY 2237
0.916	1.474	KY 480 (Cedar Grove Road)	Eastern terminus
1.000 mi = 1.609 km; 1.000 km = 0.621 mi