Lausanne railway station (French: Gare de Lausanne) is the main intercity and regional railway station for the city of Lausanne, Vaud, Switzerland. It is often known as Lausanne CFF to distinguish it from others in the town.

Lausanne is a through station, which sits at the junction of the Simplon, Lausanne–Bern, and Lausanne–Geneva railway lines. Due to this, express passenger trains are available to a wide variety of destinations across the country.

Passenger trains are primarily run by Swiss Federal Railways (SBB CFF FFS), with additional international trains run by companies from neighbouring France (TGV Lyria).

There is also a network of local services from Lausanne, primarily as part of the RER Vaud, and platforms for line 2 of the Lausanne Métro. The metro station, Lausanne-Gare, was opened on 27 October 2008.

Passenger facilities include Bureau de change, left luggage and lost property offices.

Significant improvements are planned for the station by 2020. A third subway is to be constructed for platform access, along with longer platforms to allow larger trains. A new tunnel is also to be built for the Lausanne Métro directly underneath the Renens (West) end of the main line station, with new métro platforms directly connected to the subway, removing the need for some métro passengers to cross the square in front of the station.

As of the December 2023 timetable change, the following services call at Lausanne:

• TGV Lyria: six trains per day to Paris-Lyon via either Vallorbe or Genève-Cornavin.
• EuroCity: four trains per day between Genève-Cornavin and Milano Centrale, with one train continuing from Milano Centrale to Venezia Santa Lucia.
• InterCity: hourly service to Geneva Airport and St. Gallen and half-hourly service to Zürich Hauptbahnhof.
• Geneva Airport–Bern–Zürich HB–St. Gallen
• Geneva Airport/Lausanne–Biel/Bienne–Zürich HB (–St. Gallen/Rorschach)
• InterRegio:
• Geneva Airport–Bern–Luzern
• Geneva Airport–Lausanne–Brig
  • half-hourly service between Geneva Airport and Brig.
  • hourly service between Geneva Airport and Lucerne.
  • two-round trips on weekdays to Neuchâtel.
• RegioExpress:
  • half-hourly service (hourly on weekends) between Annemasse and Vevey, and hourly service from Vevey to St-Maurice. On weekends, hourly service to Geneva Airport.
  • single daily round-trip between Renens VD and St-Maurice.
• RER Vaud:
  • R1 / R2: half-hourly service to Grandson and to Cully on weekdays.
  • R3 / R4: half-hourly (hourly on weekends) service between Vallorbe and Aigle; hourly service to Le Brassus; hourly service to St-Maurice on weekdays.
  • R5 / R6: half-hourly service between Allaman and Palézieux; weekday rush-hour service continues from Palézieux to Romont FR.
  • R9: hourly service to Kerzers.

• 
  Lausanne station from Place de la Gare
• 
  Lausanne station, looking East.
• 
  View under overall canopy (and a Swiss railway clock), looking East.
• 
  Lausanne Metro Line m2 platforms & coach

• History of rail transport in Switzerland
• Rail transport in Switzerland

• Lausanne railway station – SBB
• Interactive station plan (Lausanne)