Mšené-lázně is a spa municipality and village in Litoměřice District in the Ústí nad Labem Region of the Czech Republic. It has about 1,900 inhabitants.

The villages of Brníkov, Ječovice, Podbradec, Ředhošť and Vrbice are administrative parts of Mšené-lázně.

Mšené-lázně is located about 19 kilometres (12 mi) south of Litoměřice and 35 km (22 mi) northwest of Prague. It lies in a flat and mainly agricultural landscape in the Lower Ohře Table. The highest point is at 294 m (965 ft) above sea level. The stream Mšenský potok flows through the municipality.

The first written mention of Mšené is from 1262.

Historical population

Year Pop. ±% 1869 2,609 —     1880 3,021 +15.8% 1890 3,139 +3.9% 1900 3,313 +5.5% 1910 3,397 +2.5%	Year Pop. ±% 1921 3,445 +1.4% 1930 3,098 −10.1% 1950 2,336 −24.6% 1961 2,119 −9.3% 1970 1,891 −10.8%	Year Pop. ±% 1980 1,677 −11.3% 1991 1,576 −6.0% 2001 1,584 +0.5% 2011 1,718 +8.5% 2021 1,782 +3.7%
Source: Censuses

Mšené Spa was founded in 1796. The local water is rich in iron and other minerals. The spa treat especially disorders of muscular system and nerves.

Mšené-lázně is located on the railway line from Roudnice nad Labem to Libochovice. Historic trains run on it and it is only in operation during the summer tourist season on weekends.

Among the main landmarks of Mšené-lázně are Mšené Castle, Chapel of the Saint John of Nepomuk and the town hall.

A fortress, probably built around 1400, was rebuilt into the early Baroque castle in 1660. It was modified in 1748 and then rebuilt in the Neo-Renaissance style at the end of the 19th century. Today it is privately owned and inaccessible.

The set of spa buildings from 1796 is protected as a cultural monument. At the beginning of the 20th century, they were rebuilt in their present form. They combine different architectural styles: late Baroque, Neoclassicism, Art Nouveau, folk art and modern architecture.

The Church of Saint Barbara is located in Ječovice. It was originally a Gothic church, probably from the 14th century. In 1783, it was rebuilt in the late Baroque style.

The Church of Saint Giles is located in Ředhošť. It was built in the Romanesque style, probably in the 12th century, and extended in the 14th century. Its present appearance is the result of Baroque modifications from the second half of the 18th century, but the Romanesque tower has been preserved.

• František Bayer (1854–1936), zoologist and paleontologist
• Antonín Hudeček (1872–1941), landscape painter

• Official website