Marchigüe (Spanish pronunciation: [maɾˈtʃiɣwe]), sometimes spelled Marchihue ([maɾˈtʃiwe]), is a Chilean town and commune in the Cardenal Caro Province of Chile's sixth region of O'Higgins.
According to the 2002 census of the National Statistics Institute, Marchigüe spans an area of 659.9 km (255 sq mi) and has 6,904 inhabitants (3,549 men and 3,355 women). Of these, 2,208 (32%) lived in urban areas and 4,696 (68%) in rural areas. The population grew by 11.2% (695 persons) between the 1992 and 2002 censuses.
As a commune, Marchigüe is a third-level administrative division of Chile administered by a municipal council, headed by an alcalde who is directly elected every four years. The 2021-2024 alcalde is Héctor Cristian Salinas Herrera.