Medekšiai (formerly Russian: Медекши, Polish: Medeksze) is a village in Kėdainiai district municipality, in Kaunas County, in central Lithuania. According to the 2011 census, the village had a population of 184 people. It is located 5 kilometres (3.1 mi) from Kėdainiai, by the Šerkšnys river, alongside the Jonava-Šeduva (KK144) road. A phosphogypsum waste dump of "Lifosa" fertilizer factory is located next to Medekšiai.

Medekšiai has been known since the 15th century. King Jogaila presented the village to a certain Proszczy whose nickname was Medekša. Pranciškus Medekša, a judge of Kovensky Uyezd, had been native of this family. In the end of the 19th century Medekšiai was a property of the Geištarai. Činkiai village and Slabadėlė folwark belonged to the Medekšiai Manor.

During the Soviet era, Medekšiai was a subsidiary settlement of the "Spike" kolkhoz.

Historical population

Year Pop. ±% p.a. 1902 99 —     1923 111 +0.55% 1959 277 +2.57% 1970 313 +1.12% 1979 295 −0.66%	Year Pop. ±% p.a. 1986 245 −2.62% 1989 225 −2.80% 2001 202 −0.89% 2011 184 −0.93%
Source: 1902, 1923, 1959 & 1970, 1979, 1989, 2001, 2011

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  Medekšiai from Nociūnai side
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  A monument to the forefathers of poet Justinas Marcinkevičius
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  "Lifosa" phosphogypsum "mountains"