Mission Valley Center station is a station on San Diego Trolley's Green Line. The street-level station has side platforms. It is located near Camino De La Reina between Mission Center Road and Camino Del Este. The station is located next to the Mission Valley mall and serves a massive commercial corridor in the Mission Valley East neighborhood.

Prior to July 2005, this station was served by the Blue Line until service between Old Town Transit Center and Mission San Diego was replaced by the Green Line upon its introduction in conjunction with the opening of the Mission Valley East extension.

There are two tracks, each served by a side platform.

Side platform, doors will open on the right
Westbound	← Green Line toward 12th & Imperial (Hazard Center)
Eastbound	→ Green Line toward El Cajon (Rio Vista) →
Side platform, doors will open on the right

• List of San Diego Trolley stations