Route 105 is a highway in Mississippi County, Missouri. Its northern terminus is at Interstate 57/U.S. Route 60 in Charleston; its southern terminus is at Route 80 in East Prairie. Other than the two termini, no other towns are on the route.

Route description

This section is empty. You can help by adding to it. (May 2021)

History

In 1924, Route 55 was designated along a concrete road starting from Benton to Wolf Island. A spur of Route 55, Route 55A, was designated one year later to a concrete road. Its western terminus was at the New Madrid–Mississippi county line, and its eastern terminus was at Route 55 north of East Prairie.

Major intersections

The entire route is in Mississippi County.

Location	mi	km	Destinations	Notes
East Prairie	0.000	0.000	Route 80 (Washington Avenue)
​	2.315	3.726	Route 102
​	3.951	6.359	Route 75 – Anniston
​	5.427	8.734	Route C / Route D
Charleston	9.419– 9.524	15.158– 15.327	I-57 / I-57 BL / US 60 – Sikeston, Cairo, IL	Southern end of I-57 Business concurrency
	10.534	16.953	I-57 BL / US 62 / Route 77 (Marshall Street) / Route N (Main Street)	Northern end of I-57 Business concurrency
1.000 mi = 1.609 km; 1.000 km = 0.621 mi