Pescara Centrale railway station (Italian: stazione ferroviaria di Pescara Centrale), also known as Pescara railway station (Italian: stazione ferroviaria di Pescara), is the main railway station of Pescara. The station lies on the Adriatic line from Rimini to Lecce and the trans-Apennine line to Rome. It serves an average of 3.5 million people per year and is a 5-minute walk to the city's main street and to the beach.

The commercial area of the passenger building is managed by Centostazioni SpA, whereas the Italian Railway Network (RFI) is responsible for the railway infrastructure.

The former headquarters of Pescara Central Station was a nineteenth-century palace at the same site. The initial draft of a new passenger building was drawn up in 1962 by Corrado Cameli Service Work for the FS. This draft proposed a steel-frame structure of the new station building, but changed to pre-stressed concrete in 1970, when structural calculations were carried out by the Studio Engineer Giovanni Cerasoli and Piero di Pescara, with the advice from the engineer Carlo Guidi Baskets. The modern-day building is one of the earliest constructions to be made of pre-stressed concrete among Italian railway stations.

The new station building was completed in 1987, when all eight railway tracks in and out of the station being raised to viaduct levels to avoid ground level-crossings.

The station is served by the following services (incomplete):

• High speed services (Frecciarossa) Milan - Bologna - Ancona - Pescara - Foggia - Bari
• High speed services (Frecciabianca) Milan - Parma - Bologna - Ancona - Pescara - Foggia - Bari - Brindisi - Lecce
• High speed services (Frecciabianca) Milan - Parma - Bologna - Ancona - Pescara - Foggia - Bari - Taranto
• High speed services (Frecciabianca) Turin - Parma - Bologna - Ancona - Pescara - Foggia - Bari - Brindisi - Lecce
• High speed services (Frecciabianca) Venice - Padua - Bologna - Ancona - Pescara - Foggia - Bari - Brindisi - Lecce
• Intercity services Bologna - Rimini - Ancona - Pescara - Foggia - Bari - Brindisi - Lecce
• Intercity services Bologna - Rimini - Ancona - Pescara - Foggia - Bari - Taranto
• Night train (Intercity Notte) Milan - Parma - Bologna - Ancona - Pescara - Foggia - Bari - Brindisi - Lecce
• Night train (Intercity Notte) Milan - Ancona - Pescara - Foggia - Bari - Taranto - Brindisi - Lecce
• Night train (Intercity Notte) Turin - Alessandria - Bolgona - Ancona - Pescara - Foggia - Bari - Brindisi - Lecce
• Express services (Regionale Veloce) Milan - Bologna - Rimini - Ancona - Pescara (weekends only)
• Regional services (Treno regionale) Rimini - Pesaro - Ancona - Civitanova Marche - San Benedetto del Tronto - Pescara
• Regional services (Treno regionale) Pescara - Chieti - Sulmona - Avezzano - Carsoli - Tivoli - Rome
• Regional services (Treno regionale) Teramo - Giulianova - Pescara - Chieti - Sulmona - Avezzano
• Regional services (Treno regionale) Teramo / San Benedetto del Tronto - Pescara - Ortona - San Vito Lanciano - Termoli
• Local services (Treno regionale) San Benedetto del Tronto - Pescara - Ortona San Vito Lanciano - Lanciano

Preceding station		Trenitalia		Following station
Ancona toward Milano Centrale		Frecciarossa		Foggia toward Bari Centrale
Ancona toward		Frecciabianca		Termoli toward
Ancona toward		Frecciabianca		Termoli toward
Ancona toward		Frecciabianca		Termoli toward
Ancona toward		Frecciabianca		Termoli toward
Giulianova toward Bologna Centrale		InterCity		Vasto-San Salvo toward Lecce
Giulianova toward Bologna Centrale		InterCity		Vasto-San Salvo toward Taranto
Ancona toward Milano Centrale		Intercity Notte		Foggia toward Lecce
Ancona toward Milano Centrale		Intercity Notte		San Severo toward Lecce
Ancona toward Torino Porta Nuova		Intercity Notte		Termoli toward Lecce
Montesilvano toward Rimini		Treno regionale		Terminus
Terminus		Treno regionale		Pescara Porta Nuova toward Roma Tiburtina
Montesilvano toward Teramo		Treno regionale		Pescara Porta Nuova toward Avezzano
Preceding station		Ferrovia Adriatico Sangritana		Following station
Montesilvano toward Teramo		Treno regionale		Pescara Porta Nuova toward Termoli
Montesilvano toward San Benedetto del Tronto		Treno regionale		Pescara Porta Nuova toward Termoli
Montesilvano toward Teramo		Treno regionale		Pescara Porta Nuova toward Lanciano
Montesilvano toward San Benedetto del Tronto		Treno regionale		Pescara Porta Nuova toward Lanciano

The bus station is located at the front of Pescara Centrale railway station. Bus services include connections within Pescara to Chieti, Lanciano, and Abruzzo Airport (Urban Bus no. 38). Long-distance coaches to Rome-Tiburtina and Bologna have their terminus at this bus station in Pescara.

From the bus station in front of the station there has been a daily connection of ITA Airways by bus, to and from Rome Fiumicino Airport since 1 December 2022, allowing a connection with the airline's hub.

The station building hosts a ticket office, automatic ticket machines, two newspaper stands, a cafe bar, and a pharmacy. During the night hours, entry into the station building is only permitted for passengers with valid InterCity Notte (ICN) tickets.

• History of rail transport in Italy
• List of railway stations in Abruzzo
• Rail transport in Italy
• Railway stations in Italy