The Rockpile Mountain Wilderness is a wilderness area in the U.S. state of Missouri in Mark Twain National Forest. It takes its name from an ancient circle of granite rock, piled by some earlier man on top of the mountain. The namesake rock pile most likely was an Indian cairn. It is located in Madison County, Missouri, southeast of Bell Mountain and southwest of Fredericktown, Missouri. The area is primarily a broken ridge, having steep rocky slopes running from Little Grass Mountain on the north to the National Forest boundary four miles to the south.

• Bell Mountain Wilderness
• Devils Backbone Wilderness
• Hercules-Glades Wilderness
• Irish Wilderness
• Paddy Creek Wilderness
• Piney Creek Wilderness