Sępolno Wielkie [sɛmˈpɔlnɔ ˈvjɛlkʲɛ] is a village in the administrative district of Gmina Biały Bór, within Szczecinek County, West Pomeranian Voivodeship, in north-western Poland. It lies approximately 8 kilometres (5 mi) north-west of Biały Bór, 27 km (17 mi) north of Szczecinek, and 156 km (97 mi) east of the regional capital Szczecin.

For the history of the region, see History of Pomerania.

The village has a population of 360.