Santiago High School is a high school located in Garden Grove, California, and is a member of the Garden Grove Unified School District. The school's athletic teams are known as the Cavaliers. Santiago High School has been an AVID National Demonstration School since 2007 and an AVID Schoolwide Site of Distinction since 2016.

The total enrollment of Santiago High School was 2,121 students for the 2015–16 school year.

• Bert Blyleven (class of 1969) – Major League pitcher; member of the MLB Hall of Fame.
• Eddie Bravo- Brazilian Jiu Jitsu black belt Founder of 10th Planet Jiu Jitsu
• Brittany Ishibashi - Actress

Santiago hosts a range of sports including tennis, basketball, baseball, football, soccer, swim, track and field, volleyball and cross country. Practices take place every week with differing times and days depending on season, sport, and projected weather. Occasional tournaments are also held once in a while.

Santiago High School has a wide range of programs and electives for its students such as JROTC, band, choir, art, culinary, drama,avid, world languages, automechanic, robotics, engineering design, computer science, and more. Most of these programs have associated events, clubs, or higher levels such as "AP" or "college articulation" or "1P" and "2P".

• [1] - The school's official homepage
• [2] - A PDF copy of the school's 2009-2010 report card.