The Kyū-Yodo River (旧淀川, Kyū-Yodo-gawa) was the main stream of the Yodo River before 1907, when the current (new) Yodo River was constructed by a normalisation project. Now called the Kyū-Yodo River, it is a major waterway in central Osaka and the main drainage of Neyagawa river.

The name Kyū-Yodo river means former Yodo river in Japanese.

The name Kyū-Yodo River is a geological name, locally it is called by subdivision names. From the source to the mouth, it is named as follows:

This is the name for the section from the Kema Lock to the Tenjimbashi (bridge); the Japanese name is Ōkawa (大川).

This is the name for the section from the Tenjimbashi (bridge) to the Funatsubashi (bridge) along the north shore of Nakanoshima Island; the Japanese name is Dōjima-gawa (堂島川).

This is the name for the section from the Tenjimbashi (bridge) to the Funatsubashi (bridge) along the south shore of Nakanoshima Island; the Japanese name is Tosabori-gawa (土佐堀川).

This is the name for the section from the Funatsubashi (bridge) to Tempōzan, Osaka Bay; the Japanese name is Aji-gawa (安治川).

Points of interest from the source to the mouth.

Kita ward, Miyakojima ward

• Yodo River
• Kema Lock
• Kema Sakuranomiya Park
• OAP Tower
• Imperial Hotel Osaka
• National Mint Factory

Kita ward, Chūō ward

• Keihan City Mall (department store)
• Minami-Temma Park
• Nakanoshima
• Nakanoshima Park
• Osaka Stock Exchange
• Museum of Oriental Ceramics
• City Hall
• High District Court Osaka branch
• Bank of Japan Osaka branch

Fukushima ward, Kita ward, Nishi ward

• Hotarumachi
• National Museum of Art, Osaka
• Osaka Science Museum
• Rihga Royal Hotel
• Osaka International Convention Center
• Osaka Central Wholesale Market

Konohana ward, Minato ward

• Universal Studios Japan
• Osaka Aquarium Kaiyukan
• Tempōzan

For Nakanoshima area, each station of Keihan Nakanoshima Line is nearest. For Osaka Aquarium Kaiyukan and Tempōzan, Metro Ōsakakō Station is nearest.