Aliso Niguel High School (ANHS), which is part of the Capistrano Unified School District, is located in the city of Aliso Viejo, California. Most of its students reside in the communities of Aliso Viejo and Laguna Niguel. The school is a California Distinguished School, a National Blue Ribbon School, and a New American High School.

Opening its doors in 1993 with a student body of 1600, ANHS became the fourth high school in the Capistrano Unified School District.

In 1996, Aliso Niguel was selected as a California Distinguished School, the youngest school ever to be recognized as such by the State Department of Education. In 2000, Aliso Niguel High School received national recognition as a Blue Ribbon School and New American High School. In 2004, The Western Association of Schools and Colleges granted Aliso Niguel a six-year term of accreditation, which it renewed for an additional six-year period in 2010, and again in 2016.

Although the high school started small (with about 1,400 students) in their first year, the high school grew rapidly over the years, and it still continues to grow to this present day. Currently, the school has 26 portable classrooms in its southern parking lot adding to 22,080 square feet (2,051 m), and 100 permanent classrooms. The permanent buildings are 200,000 square feet (19,000 m) forming a grand total of 222,080 square feet (20,632 m) on the campus, making Aliso the largest school in the district. The campus also includes a stadium, Wolverine Stadium, with a track and multipurpose field. Wolverine Stadium, which opened in 1994, seats 2,675 people, it includes a visitor side and a larger home side for seating.

Aliso Niguel's sports teams are known as the Wolverines and compete in the Sea View League and South Coast League of the California Interscholastic Federation's Southern Section. From 1998 to 2005, they were members of the Sea View League, and in the Pacific Coast League (California) before 1998.

In 1996, the Aliso Niguel Varsity Football team went undefeated and won the CIF-SS Division VIII championship.

In 2005, The Aliso Niguel Boys Basketball team won the CIF-Southern Section Division I-A championship.

In 2012, the Aliso Niguel Girls Soccer team won the CIF Southern Section Division 1 championship. They were also named National Champions by ESPN and MaxPreps.

In 2014, the Aliso Niguel Girls Volleyball team won the CIF Southern Section championship.

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• Kathryn Plummer, Olympic silver medalist and volleyball player for NCAA Champion Stanford Cardinal women's volleyball in 2016, 2018, 2019, current pro player for Eczacıbaşı Dynavit
• Sammy Jo Prudhomme, professional soccer player
• Grant Ginder, author of The People We Hate at the Wedding
• Michelle Giuda, businesswoman
• Michael Roll, professional basketball player
• Robb MacLean, guitar and lead vocals for Limbeck
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• Blake Sabol, baseball player for the San Francisco Giants
• Skip Schumaker, former Major League Baseball outfielder and second baseman and current manager of the Miami Marlins
• Zaneta Wyne, professional soccer player English Women's Super League
• Julian Jones, assistant and "Babysitter to the Stars" for the Maloof Family
• Nicky Youre, singer and songwriter
• Noah Munck, played Gibby Gibson on Nickelodeon's iCarly, as well as "Naked Rob" on ABC's The Goldberg's

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