Arkansas Highway 5 (AR 5) is a designation for three state highways in Arkansas. The southern segment of 45.84 miles (73.77 km) runs from U.S. Route 70 (US 70) east of Hot Springs north to Interstate 430 (I-430) in Little Rock.

A northern segment of 146.63 miles (235.98 km) runs from I-57 in Cabot north to the Missouri state line, including a lengthy overlap with Highway 25 between Heber Springs and Wolf Bayou. A portion of this route is designated as part of the Sylamore Scenic Byway. This segment also contained a former spur route in Mountain Home.

The Main Street Bridge in Little Rock carries a third, unsigned, Highway 5 designation. The bridge is 0.38 miles (0.61 km) in span.

All three routes are maintained by the Arkansas Department of Transportation (ArDOT).

Highway 5 begins at an interchange with US 70 and US 70B east of Hot Springs as a two-lane freeway. The route meets Highway 7 in Fountain Lake at a roundabout and continues to northeast as a surface road. In the city of Fountain Lake, Highway 5 has a junction with Highway 128 before entering Saline County and Hot Springs Village. Continuing east, the route serves as the southern terminus for Highway 9 at Crows. Northwest of Benton, Highway 5 has a junction with Highway 298 before entering the city and passing several residential subdivisions. Near Saline Memorial Hospital, the route has a junction with I-30/US 67/US 70 and Highway 35. Highway 5 runs east as a frontage road paralleling I-30 toward Little Rock. Highway 35 runs south toward downtown Benton and eventually Sheridan and Monticello.

The route passes the Hester-Lenz House, listed on the National Register of Historic Places (NRHP), prior to the Bryant city limits. An intersection with Highway 183 (Reynolds Rd) near the historic Andrew Hunter House gives access to downtown Bryant as well as I-30. Continuing east, Highway 5 intersects Highway 835 (Woody Drive) which leads to the Alexander branch of the Arkansas Department of Human Services's Youth Service Center, after which it enters Pulaski County.

The route meets Otter Creek Road and Highway 338 (Baseline Road), both collector roads for I-30/US 67/US 70 in southwest Little Rock. Entering a suburban area, Highway 5 terminates at an interchange with I-430 and US 70.

The Main Street Bridge in Little Rock carries a hidden Highway 5 designation. The route is 0.38 miles (0.61 km) in span and multi-lane divided.

The route begins just south of I-57/US 67/US 167 at Highway 321 and Highway 367 in Cabot and runs north to cross Highway 89 and Highway 319. Highway 5 continues north to meet US 64 south of El Paso and Highway 310 near Romance. Highway 5 and Highway 310 form a concurrency that runs until Highway 36 in Rose Bud. The route continues north to Heber Springs, where it begins to concur with Highway 16/Highway 25.

Highway 5 leaves Highway 25 near Wolf Bayou, when Highway 5 begins to run with Highway 87, named Mountain View Road. The two routes meet Highway 14 in front of the Stone County Medical Center in south Mountain View. Highway 5/Highway 14/Highway 87 run briefly west to Sylamore Avenue, when they meet Highway 9. Highway 5/Highway 9/Highway 14 run north through town to Allison, when Highway 5 continues northward alone. Passing through the Ozark National Forest, Highway 5 emerges near Calico Rock. The route takes a turn northwest, concurring with Highway 177 near Norfork. Highway 5 crosses US 62 southeast of Mountain Home. The route becomes 9th Street, meeting US 62B and Highway 201 in downtown Mountain Home. Highway 5 continues northwest to Midway, after which it heads north to the Missouri state line, where it continues as Missouri Route 5.

Missouri Route 5 runs entirely across Missouri and eventually becomes Iowa Highway 5.

Highway 5 was created in 1926 as one of the original numbered state highways in Arkansas. At time of creation, Highway 5 did not extend south of Little Rock. The segment between Little Rock and Benton is the former alignment of US 67/US 70 in that area and was re-designated as Highway 5 upon completion of the freeway segment of US 67/US 70 (now I-30) in 1955.

The Arkansas State Highway Commission truncated Highway 5 at I-430 and renumbered the remainder of Stagecoach Road as US 70 on December 9, 2021 in a deal with the cities of Little Rock, North Little Rock, and Pulaski County to cover the relocation costs for Rock Region Metro as part of the "30 Crossing" project on I-30.

In 2023, a freeway was completed, connecting Highway 5 directly to the Hot Springs Bypass. Highway 5 now begins at an interchange with US 70 and US 70B east of Hot Springs and continues north to where it meets Highway 7 in Fountain Lake. The new section was originally scheduled to open in fall 2022; however, the national supply chain crisis delayed the project. Issues with a retaining wall also contributed to the delay, moving the completion date to September 18, 2023. The roadway is a two-lane freeway.

County	Location	mi	km	Exit	Destinations	Notes
Garland	​	0.00	0.00	–	US 70 west to US 270 – Glenwood, Mount Ida	Southern terminus
	​			11	US 70 east / US 70B west – Little Rock, Hot Springs	Southbound exit and northbound entrance; signed as exits 11A (east) and 11B (west); eastern terminus and exit 6B on US 70B
	​			–	Mill Creek Road
	​	5.82	9.37	Northern end of freeway section
					AR 7 – Hot Springs, Hot Springs Village, Russellville	Roundabout
	Fountain Lake	9.58	15.42		AR 128 east	Western terminus of AR 128
Saline	Crows	19.73	31.75		AR 9 north – Perryville	Southern terminus of AR 9
	​	28.60	46.03		AR 298 west	Eastern terminus of AR 298
	Benton	32.41	52.16		I-30 (US 67 / US 70) / AR 35 south – Benton, UALR Benton Center, Little Rock, Texarkana	Interchange; northern terminus of AR 35; exit 117 on I-30
		34.03	54.77		I-30 (US 67 / US 70) / Congo Road – Little Rock, Texarkana	Interchange; exit 118 on I-30
		36.77	59.18		To I-30 (US 67 / US 70)	Access via Alcoa Road
	Bryant	38.97	62.72		AR 183 south (Reynolds Road)	Northern terminus of AR 183
		40.31	64.87		Woody Drive (AR 835 west) – Arkansas Juvenile Assessment and Treatment Center	Former AR 111
Pulaski	Little Rock	45.01	72.44		AR 338 east (Baseline Road)	Western terminus of AR 338
		45.84	73.77		I-430 / US 70 (Stagecoach Road)	Northern terminus; exit 1 on I-430
		Gap in route
		0.00	0.00		Scott Street	Continuation south
	Little Rock–North Little Rock line			Main Street Bridge over the Arkansas River
	North Little Rock	0.38	0.61		Main Street	Continuation north
Gap in route
Lonoke	Cabot	0.00	0.00		AR 321 north / AR 367 north – Cabot	Southern terminus; southern termini of AR 321 and AR 367
		0.14	0.23		I-57 / US 67 / US 167 – Little Rock, Beebe, Cabot, St. Louis, Bald Knob, Jacksonville	Exit 16 on I-57
Lonoke–Pulaski county line		2.73	4.39		AR 89 to I-57 / US 67 (US 167) / AR 107
Lonoke	​	8.22	13.23		AR 319
White	​	11.97	19.26		US 64 – Conway, Beebe
	​	20.83	33.52		AR 310 west – Mount Vernon	Eastern terminus of AR 310
	​	21.57	34.71		AR 31 south – Romance, Beebe	Northern terminus of AR 31
	Rose Bud	28.65	46.11		AR 36 west to AR 124 – Fairfield Bay, Mount Vernon	Southern end of AR 36 concurrency
		28.70	46.19		AR 36 east – Searcy	Northern end of AR 36 concurrency
Cleburne	​	38.58	62.09		AR 16 west / AR 25 south – Quitman, Greers Ferry	Southern end of AR 16/AR 25 concurrency
	see AR 25 (mile 25.62–45.69)
	Wolf Bayou	58.61	94.32		AR 25 north (Heber Springs Road) – Batesville	Northern end of AR 25 concurrency
Stone	Mountain View	80.43	129.44		AR 14 east – Batesville	Southern end of AR 14 concurrency
		82.11	132.14		AR 9 south to AR 66 – Mountain View Business District	Southern end of AR 9 concurrency
		83.26	133.99		AR 382 west – Ozark Folk Center State Park	Eastern terminus of AR 382
	Allison	87.85	141.38		AR 9 north / AR 14 west – Fifty Six, Melbourne, Blanchard Springs Caverns	Northern end of AR 9/AR 14 concurrency
	​				AR 933-2 – Sylamore Creek Access
Izard	Calico Rock	104.47	168.13		AR 56 east – Brockwell, Batesville, Business District	Western terminus of AR 56
Baxter	Norfork	115.16	185.33		AR 177 south (Shed Road)	Northern terminus of AR 177
		117.98	189.87		AR 341 south to AR 201	Northern terminus of AR 341
	Salesville	120.07	193.23		AR 177 north – Jordan, Norfork Dam, Quarry Cove Recreation Areas	Southern terminus of AR 177
	​	124.17	199.83		AR 342 east (Sycamore Springs Road) – Georges Cove Recreation Area	Western terminus of AR 342
	​	124.61	200.54		AR 341 north (Tracy Ferry Road) – Tracy Recreation Area	Southern terminus of AR 341
	​	128.89	207.43		US 62 / US 412	Interchange
	Mountain Home	130.42	209.89		AR 201 south (College Street)	Southern end of AR 201 concurrency
		130.78	210.47		US 62B west	Southern end of US 62B concurrency
		130.90	210.66		AR 178 west (West 6th Street)	Eastern terminus of AR 178
		131.22	211.18		US 62B east	Northern end of US 62B concurrency
		131.29	211.29		AR 201 north	Northern end of AR 201 concurrency
	Midway	137.26	220.90		AR 126 south / AR 178 east – Whiteville, Gassville, Ozark Regional Airport	Southern end of AR 178 concurrency; northern terminus of AR 126
		137.36	221.06		AR 178 west – Lakeview, Bull Shoals, Bull Shoals-White River State Park	Northern end of AR 178 concurrency
	​	145.42	234.03		AR 202 west – Oakland, Oakland Park, Ozark Isle Park	Eastern terminus of AR 202
	​	146.63	235.98		Route 5 north – Gainesville	Continuation into Missouri
1.000 mi = 1.609 km; 1.000 km = 0.621 mi       Concurrency terminus

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