Desmond's Building, also known as Desmond's Department Store, is a historic six-story building located at 614 S. Broadway in the Broadway Theater District in the historic core of downtown Los Angeles.

Desmond's Building, built in 1924, was designed by Albert C. Martin Sr., the architect responsible for several Los Angeles landmarks, including Million Dollar Theatre, City Hall, St. Vincent de Paul Church, May Company Building, and more. This building was originally the flagship location of Desmond's, who vacated it in 1981.

In 1979, the Broadway Theater and Commercial District was added to the National Register of Historic Places, with this building listed as a contributing property in the district. In 2020, the building was listed as Los Angeles Historic Cultural Monument #1207.

Between 2018 and 2020, the building was converted to office space with a restaurant and rooftop bar. The project, which added two floors to the top of the building in addition to a complete restoration, was budgeted at $12 million ($14.6 million in 2023).

In 2024, the building was sold for $16 million ($16 million in 2023).

Desmond's Building was designed in the Spanish Baroque style and features twisting columns, balconies, and an ornamental pediment. It was built with concrete and has a polychrome terra cotta facade. In 1933, the façade was redone in the Beaux Arts style.

• List of contributing properties in the Broadway Theater and Commercial District
• List of Los Angeles Historic-Cultural Monuments in Downtown Los Angeles