U.S. Route 69 (US 69) is a major north-south U.S. Highway in the U.S. state of Oklahoma. It extends the corridor formed by U.S. Route 75 in Texas, from Dallas northeast via McAlester and Muskogee to the Will Rogers Turnpike (Interstate 44) near Vinita. From Vinita to the Kansas state line, US-69 generally parallels the turnpike along old U.S. Highway 66.

U.S. Highway 69 crosses the Red River to enter Bryan County, Oklahoma concurrent with US-75 3 miles (4.8 km) south of Colbert. The first few miles of highway north of the state line are freeway-grade, featuring three interchanges, including one at State Highway 91. Near Calera, the route downgrades to an expressway. On the west side of Durant, however, US-69/75 becomes a freeway again, beginning with an interchange with U.S. Highway 70, and followed by an interchange with SH-78. The freeway continues northeast, providing access to Armstrong, Caddo, and SH-22 before becoming an expressway once again at the Atoka County line.

In Atoka County, US-69/75 bypass Caney and Tushka to the west before coming to the SH-3/7 junction in the county seat of Atoka, Oklahoma; at this junction, SH-3 joins with the U.S. routes while SH-7 has its eastern terminus. North of this interchange, US-75 and SH-3 split off, leaving US-69 without any concurrent routes for the first time since crossing the Red River. Seven miles (11.3 km) northwest of Atoka, US-69 begins another concurrency, this time with SH-43, near Stringtown. The two routes run along the east shore of Atoka Lake before SH-43 splits off to the west. US-69 then heads through unincorporated Chockie, and then serves as the eastern terminus of SH-131 just south of the Pittsburg County line.

US-69 then crosses into Pittsburg County. US-69 runs just east of Kiowa, where it intersects State Highway 63 at its western terminus. US-69 runs along the east edge of the McAlester Army Ammunition Plant, which it provides access to via an interchange near Savanna. It then has an interchange with the Indian Nation Turnpike, after which it enters McAlester. US-69 mostly runs along the east side of McAlester, the county seat of Pittsburg County, with the downtown area being served by U.S. Highway 69 Business. The main route of US-69 has an interchange with US-270/SH-1/SH-31. North of McAlester, US-69 reunites with its business loop at an interchange which also serves as the southern terminus of SH-113. US-69 regains freeway status at this interchange, and begins crossing over several arms of Lake Eufaula. US-69 provides several interchanges for lake access. Other interchanges serve the northern terminus of SH-113 (which has both termini at US-69) and the western terminus of SH-9A. US-69 then crosses the main channel of the Canadian River into McIntosh County.

Soon after crossing into McIntosh Co., US-69 serves the county seat of Eufaula, with exits for US-69's Eufaula business loop and State Highway 9. The freeway then has an exit to the southern terminus of State Highway 150. US-69 then meets Interstate 40 at a cloverleaf interchange and has a pair of interchanges serving Checotah. The route then enters Muskogee County, where it has exits for Oktaha and Wainwright. The freeway then ends near Summit, and US-69 continues north at-grade.

US-69 meets the western terminus of State Highway 165 as it enters Muskogee. The route runs along the west side of the city, intersecting U.S. Highway 64 and briefly concurring with US-62. US-69 then crosses the Arkansas River into Wagoner County. Shortly after entering the county, the highway has an interchange with the Muskogee Turnpike, northeast of Tullahassee. In Wagoner, US-69 meets SH-51. It then enters Mayes County.

In Mayes County, the highway has an interchange with US-412 south of Chouteau. US-69 creates a spur to Sportsman Acres, SH-69A. The route then intersects SH-20 in Pryor and SH-28 in Adair. US-69 leaves Mayes County and enters Craig County south of Big Cabin. As the route approaches Big Cabin, signage affixed to the side of parked truck trailers warns of a speed zone, due to Big Cabin's former speed trap status. The trap was shut down by the Oklahoma Department of Public Safety on August 1, 2005. Just north of the town, US-69 has the first of three interchanges with Interstate 44, the Will Rogers Turnpike. After crossing the turnpike, the route begins a concurrency with US-60 into Vinita. The two U.S. routes serve as the southern terminus of SH-2 there. East of town, another access point to the turnpike is offered. SH-82's northern terminus lies 4 miles (6.4 km) east of this.

US-60/69 cut the northwest corner of Delaware County, entering just west of the northern terminus of State Highway 85. The routes then cross into Ottawa County, passing through Afton, before US-59 joins the concurrency. Just north of this, US-60 splits off at an interchange which also serves as the third entry to the Will Rogers Turnpike. Near Narcissa, US-59/69 passes the east end of SH-25. US-59 then splits off to follow SH-10 westbound, while SH-10 eastbound follows US-69 into Miami. The two routes concur briefly before splitting near downtown Miami, where US-69 forms a one-way couplet. After reuniting north of downtown, US-69 serves as a major arterial through the city, before leaving town and arcing northeast through North Miami and Commerce. US-69 then spawns U.S. Highway 69 Alternate to Quapaw and Baxter Springs, Kansas. The main route turns north, running through the Tar Creek Superfund site and abandoned community of Picher, before leaving Oklahoma and entering the state of Kansas.

This section needs expansion. You can help by adding to it. (June 2008)

U.S. Highway 69 in Oklahoma generally follows the old Texas Road.

All of US-69 between the US-60 junction west of Vinita and the western terminus of US-69 ALT is part of the former route of Route 66.

The Intermodal Surface Transportation Efficiency Act of 1991 requires the United States Secretary of Transportation to designate U.S. 69 between the Texas state line and Checotah (I-40) as an Interstate highway upon request from ODOT.

County	Location	mi	km	Exit	Destinations	Notes
Bryan	Red River	0.00	0.00		US 75 south (US 69 south) – Denison	Texas state line
	​	0.7	1.1	1	Old River Road, South Franklin Street
	Colbert	2.2	3.5	2	SH-91 – Colbert, Denison Dam
		4.0	6.4	4	North Franklin Street, Leavenworth Trail	North end of freeway; Formerly signed Platter
	Calera	8.9	14.3	8	Calera	Northbound exit and southbound entrance; south end of freeway
		9.7	15.6	10	Main Street - Calera
		10.8	17.4	11A	Rose Hill Road, South 9th Avenue	Northbound exit and southbound entrance; former US-69B/US-75B north
		11.3	18.2	11C	Calera Service Road	Southbound exit and northbound entrance
	Durant	11.7	18.8	11B	Choctaw Road – Choctaw Nation Resort	Southbound exit signed as exits 11A-B and also includes Rose Hill Road and South 9th Avenue
		12.5– 12.8	20.1– 20.6	12	US 70 – Madill, Hugo	Signed as exits 12A (east) and 12B (west)
		14.9	24.0	14	West Main Street	Former US-70
		15.6	25.1	15	University Boulevard, Westside Drive	Southbound exit only
				15	University Boulevard, Bryan Drive	Northbound exit only; access to AllianceHealth Durant
		16.6	26.7	16	Washington Avenue
		18.0	29.0	18	SH-48 north / SH-78 – Durant	SH-78 south is former US-69B/US-75B south
		19.2	30.9	19	Ury Drive	Formerly signed Armstrong, Durant State Fish Hatchery
	​	22.8	36.7	23	County Road N3760	Formally signed Stockyard
	Caddo	27.2	43.8	27	SH-22 – Caddo, Kenefic	North end of freeway
Atoka	Atoka	46.3	74.5		SH-3 east / SH-7 west / SH-3 Byp. west (13th Street)	Southern end of SH-3 concurrency; eastern terminus of SH-7
		47.2	76.0		US 75 north / SH-3 west – Coalgate, Ada	Northern end of US-75/SH-3 concurrency
	Stringtown	54.5	87.7		SH-43 east – Daisy	Southern end of SH-43 concurrency
	​	59.6	95.9		SH-43 west – Coalgate	Northern end of SH-43 concurrency
	​	70.0	112.7		SH-131 west – Wardville
Pittsburg	Kiowa	74.5	119.9		SH-63 east (8th Street) – Pittsburg, Haileyville
	Savanna	82.7	133.1	82	U.S. Army Ammunition Plant	Interchange
	​	85.7– 85.9	137.9– 138.2		Indian Nation Turnpike – Henryetta, Tulsa, Antlers, Hugo	Indian Nation Turnpike exit 63
	McAlester	87.8	141.3	87	US 69 Bus. north – McAlester	No northbound entrance
		89.7	144.4	89	Village Boulevard	South end of expressway
		90.3	145.3	90	Peaceable Road, Comanche Avenue
		91.5– 91.7	147.3– 147.6	91	US 270 / SH-1 / SH-31 – McAlester, Krebs, Wilburton	Signed as exits 91A (east) and 91B (west)
		92.2	148.4	92	Electric Avenue
		93.4	150.3	93	Hereford Lane	North end of expressway
	​	96.4	155.1	96	US 69 Bus. south / SH-113 north – Indianola, McAlester	South end of freeway
	​	99.8	160.6	100	Shady Grove Road	Formerly Coal Creek Road
	​	102.8	165.4	103	Rock Creek Road
	​	105.3	169.5	106	Nale Road, Crowder
	Canadian	110.7	178.2	109	SH-113 – Canadian, Indianola, Arrowhead State Park
	​	114.7	184.6	113	SH-9A east to SH-9 – Carlton Landing, Stigler
McIntosh	​	118.2	190.2		US 69 Bus. north – Eufaula	northbound exit and southbound entrance
	Eufaula	120.9	194.6		SH-9 – Eufaula, Wetumka
	​	121.4	195.4		US 69 Bus. south – Eufaula
	​	125.8	202.5		SH-150 / Texanna Road – Lake Eufaula State Park
	​	128.6	207.0		Onapa Road
	​	132.6– 133.1	213.4– 214.2		I-40 (US 69 Bus. north) – Oklahoma City, Fort Smith	I-40 exits 264 A–B
	Checotah	133.9	215.5		US 266 – Checotah
		135.9	218.7		US 69 Bus. south – Checotah, Rentiesville
Muskogee	​	141.6	227.9		Oktaha, Rentiesville
	​	144.2	232.1		Wainwright
	​	150.6	242.4		Summit	At-grade intersection; north end of freeway; former US-69 south
	Muskogee	152.9	246.1		US 64 east to SH-165 (Peak Boulevard) – Tahlequah	Interchange; southern end of US-64 concurrency
		155.9	250.9		US 62 west / US 64 west / SH-16 west / US 62 Bus. east / US 64 Bus. east (Okmulgee Avenue)	Northern end of US-64 concurrency, southern end of US-62/SH-16 concurrency
		156.9	252.5		US 62 east / SH-16 east (Shawnee Bypass) – Tahlequah	Northern end of US-62/SH-16 concurrency
Wagoner	​	161.7	260.2		SH-51B west – Porter
	​	161.9	260.6		SH-351 (Muskogee Turnpike) – Tulsa, Fort Smith	SH-351 exit 26
	Wagoner	170.3	274.1		SH-51 – Coweta, Wagoner
Mayes	Chouteau	185.0– 185.2	297.7– 298.1		US 412 – Tulsa, Locust Grove	Interchange
	​	190.9	307.2		SH-69A east – MidAmerica Industrial Park
	Pryor	195.2	314.1		SH-20 (Graham Avenue)
	Adair	204.7	329.4		SH-28 (Main Street) – Chelsea, Langley
Craig	Big Cabin	214.4	345.0		I-44 (Will Rogers Turnpike)	I-44 exit 283
	​	218.7	352.0		US 60 west – Chelsea	Southern end of US-60 concurrency
	Vinita	222.5	358.1		SH-2 north (Wilson Street)	Southern terminus of SH-2
	​	223.5	359.7		I-44 (Will Rogers Turnpike)	I-44 exit 289
	​	227.9	366.8		SH-82 south – Langley
Delaware	​	232.4	374.0		SH-85 south – Bernice	Northern terminus of SH-85
Ottawa	​	239.7	385.8		US 59 south – Grove	Southern end of US-59 concurrency
	​	240.4	386.9		US 60 east	Interchange; northern end of US-60 concurrency
	​	240.6	387.2		I-44 (Will Rogers Turnpike) – Tulsa, Joplin	I-44 exit 302
	Narcissa	246.3	396.4		SH-25 west (150 Road) – Bluejacket	Eastern terminus of SH-25
	​	250.6	403.3		US 59 north / SH-10 west – Welch, Lenapah	Northern end of US-59 concurrency, southern end of SH-10 concurrency
	Miami	252.4	406.2		SH-125 south (Main Street) – Fairland, Grove	Northern terminus of SH-125; does not intersect US-69 south ('A' Street SW)
		252.5	406.4		SH-10 east (Steve Owens Boulevard)	Northern end of SH-10 concurrency
	​	259.0	416.8		SH-69A south to I-44	Northern terminus of SH-69A
	​	259.6	417.8		US 69 Alt. north – Quapaw
	​	260.82	419.75		US-69 north / K-7 north – Columbus	Kansas state line
1.000 mi = 1.609 km; 1.000 km = 0.621 mi       Concurrency terminus       Incomplete access       Proposed        Tolled

U.S. Route 69
Previous state: Texas	Oklahoma	Next state: Kansas